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对抗关节炎的精油和生物活性成分:关于其治疗潜力的新视角。

Essential Oils and Bioactive Components against Arthritis: A Novel Perspective on Their Therapeutic Potential.

作者信息

Marrelli Mariangela, Amodeo Valentina, Perri Maria Rosaria, Conforti Filomena, Statti Giancarlo

机构信息

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy.

出版信息

Plants (Basel). 2020 Sep 23;9(10):1252. doi: 10.3390/plants9101252.


DOI:10.3390/plants9101252
PMID:32977657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7598204/
Abstract

Essential oils (EOs) are known to possess a number of beneficial properties. Their antimicrobial, anti-inflammatory, antioxidant, antidiabetic, and cancer-preventing activities have been extensively reported. Due to their wide use as food preservers and additives, as well as their use in agriculture, perfumes, and make-up products, these complex mixtures of volatile compounds have gained importance from a commercial point of view, not only in the pharmaceutical industry, but also in agronomic, food, cosmetic, and perfume industries. An analysis of the recent scientific literature allowed us to highlight the presence of an increasing number of studies on the potential antiarthritic properties of EOs and their main constituents, which seems to suggest a new interesting potential therapeutic application. The aim of this review is to examine the current knowledge on the beneficial effects of essential oils in the treatment of arthritic diseases, providing an overview of the reports on the in vivo and in vitro effects of EOs. Furthermore, this review critically examines the recent findings on the potential roles of the main components of EOs in the exerted beneficial effects. Obtained negative results are also reported.

摘要

精油(EOs)具有多种有益特性。其抗菌、抗炎、抗氧化、抗糖尿病和防癌活性已被广泛报道。由于它们被广泛用作食品防腐剂和添加剂,以及用于农业、香水和化妆品中,这些挥发性化合物的复杂混合物不仅在制药行业,而且在农艺、食品、化妆品和香水行业,从商业角度来看都变得越来越重要。对近期科学文献的分析使我们能够突出越来越多关于精油及其主要成分潜在抗关节炎特性的研究,这似乎暗示了一种新的有趣的潜在治疗应用。本综述的目的是审视目前关于精油在治疗关节炎疾病方面有益作用的知识,概述关于精油体内和体外作用的报告。此外,本综述批判性地研究了精油主要成分在发挥有益作用方面潜在作用的最新发现。还报告了获得的负面结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c28/7598204/9195cde482f1/plants-09-01252-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c28/7598204/f1e4401d1cde/plants-09-01252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c28/7598204/9195cde482f1/plants-09-01252-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c28/7598204/f1e4401d1cde/plants-09-01252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c28/7598204/9195cde482f1/plants-09-01252-g002.jpg

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Essential Oils and Bioactive Components against Arthritis: A Novel Perspective on Their Therapeutic Potential.

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[1]
Role of plant phytochemicals/extracts for the control of Dermanyssus gallinae in poultry and its zoonotic importance.

Poult Sci. 2025-4

[2]
Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review.

Antibiotics (Basel). 2025-1-10

[3]
Enhancing anti-inflammatory effect of brucine nanohydrogel using rosemary oil: a promising strategy for dermal delivery in arthritic inflammation.

3 Biotech. 2024-6

[4]
Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics.

Curr Drug Deliv. 2025

[5]
Quality Standards and Pharmacological Interventions of Natural Oils: Current Scenario and Future Perspectives.

ACS Omega. 2023-10-17

[6]
Rheumatoid Arthritis Has Won the Battle but Not the War: How Many Joints Will We Save Tomorrow?

Medicina (Kaunas). 2023-10-18

[7]
Plant ingredients in Thai food: a well-rounded diet for natural bioactive associated with medicinal properties.

PeerJ. 2023

[8]
(L.) DC. and L.: Phytochemical Profile, In Vitro Anti-Denaturation Effects and Lipase Inhibitory Activity of Two Ornamental Plants Traditionally Used as Herbal Remedies.

Molecules. 2022-12-21

本文引用的文献

[1]
New Arthritis Foundation Guidelines On CBD Use Could Be First Of Many More To Come.

Altern Ther Health Med. 2020-2

[2]
Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats.

J Pharmacol Exp Ther. 2020-2-6

[3]
Eucalyptol alleviates inflammation and pain responses in a mouse model of gout arthritis.

Br J Pharmacol. 2020-5

[4]
Citral-induced analgesia is associated with increased spinal serotonin, reduced spinal nociceptive signaling, and reduced systemic oxidative stress in arthritis.

J Ethnopharmacol. 2019-12-14

[5]
Anti-inflammatory effect of nano-encapsulated nerolidol on zymosan-induced arthritis in mice.

Food Chem Toxicol. 2019-11-9

[6]
Chemical variability of Rhododendron tomentosum (Ledum palustre) essential oils and their pro-apoptotic effect on lymphocytes and rheumatoid arthritis synoviocytes.

Fitoterapia. 2019-10-28

[7]
Comprehensive approaches on the chemical constituents and pharmacological properties of flowers and leaves of American basil (Ocimum americanum L).

Food Res Int. 2019-8-13

[8]
Anti-arthritic effect of β-caryophyllene and its ameliorative role on methotrexate and/or leflunomide-induced side effects in arthritic rats.

Life Sci. 2019-8-10

[9]
Nanoemulsion-loaded hydrogel coatings for inhibition of bacterial virulence and biofilm formation on solid surfaces.

Sci Rep. 2019-4-24

[10]
Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review.

Gene. 2019-3-20

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