Laboratory of Biochemistry, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90127 Palermo, Italy.
Institute of Biochemistry, Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), University of Palermo, 90127 Palermo, Italy.
Int J Mol Sci. 2021 Oct 31;22(21):11832. doi: 10.3390/ijms222111832.
Obesity is a complex disease caused by an excessive amount of body fat. Obesity is a medical problem and represents an important risk factor for the development of serious diseases such as insulin resistance, type 2 diabetes, cardiovascular disease, and some types of cancer. Not to be overlooked are the psychological issues that, in obese subjects, turn into very serious pathologies, such as depression, phobias, anxiety, and lack of self-esteem. In addition to modifying one's lifestyle, the reduction of body mass can be promoted by different natural compounds such as essential oils (EOs). EOs are mixtures of aromatic substances produced by many plants, particularly in medicinal and aromatic ones. They are odorous and volatile and contain a mixture of terpenes, alcohols, aldehydes, ketones, and esters. Thanks to the characteristics of the various chemical components present in them, EOs are used in the food, cosmetic, and pharmaceutical fields. Indeed, it has been shown that EOs possess great antibiotic, anti-inflammatory, and antitumor powers. Emerging results also demonstrate the anti-obesity effects of EOs. We have examined the main data obtained in experimental studies and, in this review, we summarize the effect of EOs in obesity and obesity-related metabolic diseases.
肥胖是一种由体内脂肪过多引起的复杂疾病。肥胖是一个医学问题,代表了发生严重疾病的重要风险因素,如胰岛素抵抗、2 型糖尿病、心血管疾病和某些类型的癌症。不可忽视的是肥胖者的心理问题,这些问题会转变成非常严重的病症,如抑郁、恐惧症、焦虑和缺乏自尊心。除了改变生活方式外,还可以通过不同的天然化合物来促进体重减轻,如精油(EOs)。EOs 是由许多植物产生的芳香物质的混合物,特别是在药用和芳香植物中。它们有气味和挥发性,并含有萜烯、醇、醛、酮和酯的混合物。由于它们所含的各种化学成分的特性,EOs 在食品、化妆品和制药领域都有应用。事实上,已经证明 EOs 具有很强的抗生素、抗炎和抗肿瘤作用。新出现的结果还表明 EOs 具有抗肥胖作用。我们研究了在实验研究中获得的主要数据,并在这篇综述中总结了 EOs 在肥胖和肥胖相关代谢疾病中的作用。