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埃塞俄比亚南部癫痫患者心理困扰的程度、症状表现及相关因素:一项横断面研究

Magnitude, Symptom Presentation and Correlates of Psychological Distress Among People with Epilepsy in Southern Ethiopia: A Cross-Sectional Study.

作者信息

Mekuriaw Birhanie, Mantefardo Bahru, Molla Alemayehu, Berhanu Getasew, Mehare Tsegaye, Belayneh Zelalem

机构信息

Department of Psychiatry, College of Health and Medical Science, Dilla University, Dilla, Ethiopia.

Department of Internal Medicine, College of Health and Medical Science, Dilla University, Dilla, Ethiopia.

出版信息

Neuropsychiatr Dis Treat. 2020 Sep 18;16:2143-2151. doi: 10.2147/NDT.S257143. eCollection 2020.

Abstract

BACKGROUND

Psychological distress is a common co-morbid condition among people with epilepsy. Untreated comorbid psychosocial problems are associated with increased morbidity and health-care costs, and negatively affects treatment outcome of people with epilepsy. Therefore, the aim of this study was to describe the prevalence of psychological distress and to identify its associated factors among people with epilepsy attending outpatient treatment in Gedeo zone public hospitals, Southern Ethiopia.

PATIENTS AND METHODS

This was an institution-based cross-sectional study conducted at Gedeo zone public hospitals from July 1st to October 1st, 2019. Self-reporting questionnaire was used to screen individuals with epilepsy for the presence of co-morbid psychological distress. A face to face interview was conducted among 321 anti-epileptic medication followers. The collected data were entered into Epi-Data version 3.1 and then exported to SPSS version 20 for further analysis. Binary logistic regression was computed to identify factors associated with psychological distress. Statistically, significant association was set at -values of <0.05 in the final model with a corresponding 95% confidence interval.

RESULTS

The prevalence of psychological distress was found to be 38.3% with 95% CI (34.1, 42.7) among people with epilepsy attending outpatient follow-up in Gedeo zone public hospitals. Being female [OR=1.57 (95% CI: 1.01-4.80)], uncontrolled seizures [OR=1.96 (95% CI: 1.21-3.18)], and longer duration of illness [OR= 3.16 (95% CI: 1.75-5.73)] were variables found to have statistically significant association with psychological distress.

CONCLUSION

The findings of this study revealed that more than one-third of people with epilepsy screened positive for psychological distress. Therefore, this demonstrates a need to design and implement programs focusing on the prevention, early screening, and providing appropriate interventions for psychological distress among people with epilepsy.

摘要

背景

心理困扰是癫痫患者中常见的共病情况。未经治疗的共病心理社会问题与发病率增加和医疗保健成本上升相关,并对癫痫患者的治疗结果产生负面影响。因此,本研究的目的是描述心理困扰的患病率,并确定埃塞俄比亚南部盖德奥地区公立医院门诊治疗的癫痫患者中其相关因素。

患者与方法

这是一项于2019年7月1日至10月1日在盖德奥地区公立医院进行的基于机构的横断面研究。使用自填问卷对癫痫患者进行共病心理困扰筛查。对321名抗癫痫药物服用者进行了面对面访谈。收集的数据录入Epi-Data 3.1版本,然后导出到SPSS 20版本进行进一步分析。计算二元逻辑回归以确定与心理困扰相关的因素。在最终模型中,统计学上显著关联设定为P值<0.05,相应的95%置信区间。

结果

在盖德奥地区公立医院接受门诊随访的癫痫患者中,心理困扰的患病率为38.3%,95%CI为(34.1,42.7)。女性[比值比=1.57(95%CI:1.01 - 4.80)]、癫痫发作未得到控制[比值比=1.96(95%CI:1.21 - 3.18)]和病程较长[比值比=3.16(95%CI:1.75 - 5.73)]被发现与心理困扰有统计学上的显著关联。

结论

本研究结果显示,超过三分之一的癫痫患者心理困扰筛查呈阳性。因此,这表明需要设计和实施针对癫痫患者心理困扰的预防、早期筛查及提供适当干预措施的项目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/925d/7509324/32eee6f5ee46/NDT-16-2143-g0001.jpg

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