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超声引导下腰椎穿刺可提高超重患者的成功率和效率。

Ultrasound-guided lumbar puncture improves success rate and efficiency in overweight patients.

作者信息

Li Yi, Carandang Raphael A, Ade Swetha, Flahive Julie, Daniello Kate

机构信息

Department of Neurology (YL, RAC, SA, KD), University of Massachusetts Medical School; Quantitative Health Sciences (JF), University of Massachusetts Medical School, Worcester; and Department of Neurology and Neurological Sciences (YL), Stanford University Medical Center, CA.

出版信息

Neurol Clin Pract. 2020 Aug;10(4):307-313. doi: 10.1212/CPJ.0000000000000725.

Abstract

BACKGROUND

Approximately 400,000 diagnostic lumbar punctures (LPs) are performed by neurologists yearly in the United States. There has been a transition from neurologists performing >40% of LPs 2 decades ago to now <15% of the time. High body mass index (BMI) is one of the key obstacles of LP for neurology residents, and the success rates drop to 58% when BMI is >35 kg/m.

METHODS

A prospective intervention study was conducted from March 2017 to March 2018 at an academic medical center. Patients were divided into ultrasound-guided LP or conventional LP. The primary outcome was the success rate of LP. The secondary outcome was the parameters regarding LP performance, the patients' feedback after procedures, and the residents' feedback about the learning modules.

RESULTS

Eighty-two patients were enrolled with inclusion criteria of age >18 years, BMI ≥25 kg/m, and able to give written informed consent. The ultrasound-guided LP group showed higher success rate (92.7% vs 68.3%, < 0.05) and less duration of time (17.02 vs 37.63 minutes, < 0.05) compared with the conventional LP group. It also showed advantages of decreased trials of needle insertions and redirections and reduced pain levels perceived by patients.

CONCLUSIONS

This study suggests that using ultrasound to localize before LP could increase the LP success rate and improve other related LP outcomes in the overweight populations. Our study also provides evidence that brief, targeted teaching modules are feasible and effective for ultrasound-guided LP training.

CLASSIFICATION OF EVIDENCE

This study provides Class III evidence that for patients with BMI ≥25 kg/m undergoing LP, ultrasound guidance increases the LP success rate.

摘要

背景

在美国,神经科医生每年大约进行40万次诊断性腰椎穿刺(LP)。从20年前神经科医生进行超过40%的腰椎穿刺,到现在这一比例降至不到15%。高体重指数(BMI)是神经科住院医师进行腰椎穿刺的关键障碍之一,当BMI>35kg/m²时,成功率降至58%。

方法

2017年3月至2018年3月在一家学术医疗中心进行了一项前瞻性干预研究。患者被分为超声引导下腰椎穿刺组或传统腰椎穿刺组。主要结局是腰椎穿刺的成功率。次要结局是与腰椎穿刺操作相关的参数、术后患者的反馈以及住院医师对学习模块的反馈。

结果

82例患者纳入研究,纳入标准为年龄>18岁、BMI≥25kg/m²且能够签署书面知情同意书。与传统腰椎穿刺组相比,超声引导下腰椎穿刺组显示出更高的成功率(92.7%对68.3%,P<0.05)和更短的操作时间(17.02对37.63分钟,P<0.05)。它还显示出减少进针和调整方向的尝试次数以及降低患者感知疼痛程度的优势。

结论

本研究表明,在腰椎穿刺前使用超声定位可提高超重人群腰椎穿刺的成功率并改善其他相关结局。我们的研究还提供了证据,表明简短、有针对性的教学模块对于超声引导下腰椎穿刺培训是可行且有效的。

证据分级

本研究提供了III级证据,即对于BMI≥25kg/m²接受腰椎穿刺的患者,超声引导可提高腰椎穿刺成功率。

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