Department of Endocrinology and Metabolism, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, 223001 Huai'an, China.
Department of Endocrinology and Metabolism, Huai'an Hospital Affiliated to Xuzhou Medical College and Huai'an Second People's Hospital, 223001 Huai'an, China.
Ann Endocrinol (Paris). 2020 Dec;81(6):561-566. doi: 10.1016/j.ando.2020.07.1109. Epub 2020 Sep 26.
The aim of the study was to analyze the correlation between income and non-alcoholic fatty liver disease (NAFLD) in a Chinese population.
subjects were divided into three groups according to liver fat content (LFC). (1) normal: LFC < 9.15%, 197 cases; (2) low LFC: LFC 9.15-20%, 532 cases; and (3) high LFC: LFC > 20%, 201 cases. Participants' clinical and social background were collected, including a routine fasting test to assess the relevant indices. Intergroup differences were compared on 1-way ANOVA, to analyze the relation between income and each index on Pearson correlation, and independent factors for LFC were identified on binary logistic regression.
(1) In retired persons, prevalence of NAFLD was greater in females (81.2%) than males (75%), but fell with age: the highest prevalence was between 40 and 49 years of age (87.5%), and the lowest above 70 years (68%). (2) Income correlated positively with triglyceride and serum uric acid levels and LFC (P < 0.05) and negatively with alanine aminotransferase (P = 0.01). (3) As income increased from level I to V, prevalence of NAFLD increased progressively (P < 0.05). In the study, LFC was taken as the dependent variable, and the traditional NAFLD risk factors and income level (I-V) were taken as independent variables. Income emerged as an independent risk factor for NAFLD. Risk in group V was 1.964-fold higher than in group I.
Prevalence of NAFLD was closely related to socio-economic level. Demographic risk factors include female gender, age 40-49 years, and monthly income > 5,000 RMB. Thus, if income is increased without improving educational level and health awareness, NAFLD prevalence will rise.
本研究旨在分析中国人群中收入与非酒精性脂肪肝（NAFLD）之间的相关性。
根据肝脂肪含量（LFC）将受试者分为三组。（1）正常：LFC<9.15%，197 例；（2）低 LFC：LFC 9.15-20%，532 例；（3）高 LFC：LFC>20%，201 例。收集参与者的临床和社会背景资料，包括常规空腹检查以评估相关指标。采用单因素方差分析比较组间差异，采用 Pearson 相关分析收入与各指标的关系，采用二元逻辑回归分析 LFC 的独立因素。
（1）在退休人群中，女性（81.2%）NAFLD 的患病率高于男性（75%），但随年龄增长而下降：40-49 岁患病率最高（87.5%），70 岁以上患病率最低（68%）。（2）收入与甘油三酯和血尿酸水平及 LFC 呈正相关（P<0.05），与丙氨酸氨基转移酶呈负相关（P=0.01）。（3）随着收入从 I 级到 V 级增加，NAFLD 的患病率逐渐增加（P<0.05）。在该研究中，LFC 为因变量，传统的 NAFLD 危险因素和收入水平（I-V）为自变量。收入是 NAFLD 的独立危险因素。V 组的风险是 I 组的 1.964 倍。
NAFLD 的患病率与社会经济水平密切相关。人口统计学危险因素包括女性、40-49 岁年龄和月收入>5000 元。因此，如果收入增加而教育水平和健康意识没有提高，NAFLD 的患病率将会上升。
