Department of General Surgery, Stanford University, 300 Pasteur Dr, Stanford, CA, 94305, USA.
Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 55905, USA.
J Gastrointest Surg. 2021 Jul;25(7):1885-1895. doi: 10.1007/s11605-020-04551-4.
The microbiome plays a major role in human physiology by influencing obesity, inducing inflammation, and impacting cancer therapies. During the 60th Annual Meeting of the Society of the Alimentary Tract (SSAT) at the State-of-the-Art Conference, experts in the field discussed the influence of the microbiome. This paper is a summary of the influence of the microbiome on obesity, inflammatory bowel disease, pancreatic cancer, cancer therapies, and gastrointestinal optimization. This review shows how the microbiome plays an important role in the development of diseases and surgical complications. Future studies are needed in targeting the gut microbiome to develop individualized therapies.
微生物组通过影响肥胖、引发炎症和影响癌症治疗，在人类生理学中发挥着重要作用。在第 60 届消化道协会（SSAT）年度会议的最新会议上，该领域的专家讨论了微生物组的影响。本文总结了微生物组对肥胖、炎症性肠病、胰腺癌、癌症治疗和胃肠道优化的影响。这篇综述表明了微生物组在疾病发展和手术并发症中的重要作用。未来需要针对肠道微生物组进行研究，以开发个体化治疗方法。
