在不同社区之间传递信息。

Translating Messages in Different Neighborhoods.

机构信息

Institut de Recherches Cliniques de Montréal (IRCM), Montréal, QC, Canada; Division of Experimental Medicine, McGill University, Montréal, QC, Canada.

Institut de Recherches Cliniques de Montréal (IRCM), Montréal, QC, Canada; Division of Experimental Medicine, McGill University, Montréal, QC, Canada; Département de Biochimie et Médecine Moléculaire, Université de Montréal, Montréal, QC, Canada.

出版信息

Dev Cell. 2020 Sep 28;54(6):691-693. doi: 10.1016/j.devcel.2020.09.006.

DOI:10.1016/j.devcel.2020.09.006

PMID:32991835

Abstract

Cellular distribution of biomolecules is important for regulating their function. In this issue of Developmental Cell, Chouaib et al., 2020 employ genetically tagged human cell lines to investigate the subcellular distribution of specific mRNAs and their encoded proteins, revealing several instances of localized translation with distinctive regulatory implications.

摘要

生物分子的细胞分布对于调节它们的功能很重要。在本期《发育细胞》中，Chouaib 等人利用基因标记的人类细胞系研究了特定 mRNA 及其编码蛋白的亚细胞分布，揭示了几个具有独特调控意义的局部翻译实例。