Modaragamage Dona Ann Christine, Abuelgasim Eyad, Abuelgasim Biyaser, Kermali Muhammed, Zahra Syeda Anum, Hewage Savini, Harky Amer
Faculty of Medicine, Imperial College London, London, United Kingdom.
Faculty of Medicine, St George's, University of London, London, United Kingdom.
J Cardiol. 2021 Apr;77(4):353-360. doi: 10.1016/j.jjcc.2020.08.011. Epub 2020 Sep 29.
Spontaneous coronary artery dissection (SCAD) is a rare but life-threatening disorder. SCAD is gaining importance as an emerging cause of acute coronary syndrome (ACS), especially in otherwise healthy young women. While SCAD and ACS show similarity in presentation, the management of SCAD differs to that of ACS. If not managed properly SCAD can lead to sudden death. This review examines the pathophysiology, clinical presentation, diagnostic algorithms, and the current and future management of SCAD.
自发性冠状动脉夹层(SCAD)是一种罕见但危及生命的疾病。作为急性冠状动脉综合征(ACS)的一个新出现的病因,SCAD正变得越来越重要,尤其是在其他方面健康的年轻女性中。虽然SCAD和ACS在临床表现上有相似之处,但SCAD的治疗与ACS不同。如果处理不当,SCAD可导致猝死。本文综述了SCAD的病理生理学、临床表现、诊断算法以及当前和未来的治疗方法。