Agras W S, Taylor C B, Kraemer H C, Southam M A, Schneider J A
Psychosom Med. 1987 May-Jun;49(3):264-73. doi: 10.1097/00006842-198705000-00005.
This article reports the findings of a study designed to evaluate the long-term effectiveness of an industry-based relaxation training program in the treatment of hypertensives whose blood pressures were not well controlled by antihypertensive medication. Following a three-stage screening process, 137 participants were randomly allocated to either relaxation training (RT) or to blood pressure monitoring (BPM) at two worksites. Participants continued to receive medical care from their primary physicians during the course of the study. The advantage for participants receiving RT, in terms of mean blood pressure changes, was modest and of short duration. However, a larger proportion of participants in the RT group came into good control (blood pressures below 90 mm Hg) than in the BPM group following treatment (69.4% vs 41.5%, p less than 0.001). This advantage continued to 24 months' follow-up (63.9% vs 47.7%, p less than 0.05). At 30 months' follow-up there was no significant difference between the groups (75.0% vs 70.8%). Within-group analyses revealed that the BPM group also achieved significant blood pressure lowering which was maintained during the study. The largest initial difference between the two groups was for individuals whose entry diastolic blood pressures were most out of control despite several years of pharmacologic treatment. No difference was found between the two groups in the prescription of antihypertensive medication.
本文报告了一项研究的结果,该研究旨在评估一项基于行业的放松训练计划对血压未通过抗高血压药物得到有效控制的高血压患者的长期疗效。经过三阶段筛选过程,137名参与者被随机分配到两个工作场所进行放松训练(RT)或血压监测(BPM)。在研究过程中,参与者继续接受其初级医生的医疗护理。就平均血压变化而言,接受RT的参与者的优势较小且持续时间较短。然而,治疗后RT组中血压得到良好控制(血压低于90毫米汞柱)的参与者比例高于BPM组(69.4%对41.5%,p小于0.001)。这一优势持续到24个月随访期(63.9%对47.7%,p小于0.05)。在30个月随访时,两组之间无显著差异(75.0%对70.8%)。组内分析显示,BPM组的血压也显著降低,且在研究期间保持稳定。两组之间最大的初始差异出现在那些尽管经过数年药物治疗但入院时舒张压仍最失控的个体中。两组在抗高血压药物处方方面未发现差异。