Hatch J P, Klatt K D, Supik J D, Rios N, Fisher J G, Bauer R L, Shimotsu G W
Biofeedback Self Regul. 1985 Jun;10(2):119-38. doi: 10.1007/BF01000749.
Fifty-two pharmacologically treated hypertensive patients were randomized to one of four treatment groups: (1) diastolic blood pressure biofeedback, (2) progressive deep muscle relaxation training, (3) self-directed relaxation training, or (4) medication alone. Data collection occurred during baseline, treatment, and 1-year follow-up phases in a laboratory, a medical clinic, and the patient's own home. Patients from all four groups combined showed mean blood pressure reductions of -10.2/-5.5 mm Hg on clinic recordings and -2.4/-.7 mm Hg on home recordings, which were maintained throughout the follow-up period. There were no significant differences among the four groups in terms of blood pressure reduction. Patients given adjunctive behavioral treatment showed significantly larger reductions in medication usage compared to patients treated with medication alone, but there were no significant differences among the three behaviorally treated groups. Patients who showed medication reductions did not show subsequent blood pressure elevation. The results suggest that combined behavioral and pharmacological therapy may be superior to pharmacological therapy alone in the treatment of essential hypertension.
52名接受药物治疗的高血压患者被随机分为四个治疗组之一：（1）舒张压生物反馈组，（2）渐进性深度肌肉放松训练组，（3）自我指导放松训练组，或（4）仅药物治疗组。数据收集在实验室、医疗诊所和患者家中的基线、治疗和1年随访阶段进行。四个组的患者综合起来，诊所记录显示平均血压降低了-10.2/-5.5毫米汞柱，家庭记录显示降低了-2.4/-.7毫米汞柱，且在整个随访期内保持稳定。四组之间在血压降低方面没有显著差异。与仅接受药物治疗的患者相比，接受辅助行为治疗的患者药物使用量显著减少，但三个接受行为治疗的组之间没有显著差异。药物使用量减少的患者随后并未出现血压升高。结果表明，在原发性高血压的治疗中，行为疗法与药物疗法相结合可能优于单纯药物疗法。
