Ahmadi Seyedeh Jahan, Farhadifar Fariba, Sharami Seyedeh Reyhaneh Yousefi, Zare Shamsi, Rezaei Masomeh, Soofizadeh Nasrin, Babaei Erfan, Moradi Ghobad, Ahmadi Amjad
Department of Obstetrics & Gynecology, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Iran J Microbiol. 2020 Aug;12(4):325-330. doi: 10.18502/ijm.v12i4.3936.
Preterm delivery is an important subject in gynecology, obstetrics and pediatrics. It is defined as regular uterine contractions every five to eight minutes or less, lasting for 30 seconds. It is associated with progressive changes in the cervix, resulting in delivery after 22 weeks and before 37 weeks of gestation. This study aimed to evaluate the role of infection in women with preterm delivery.
This case-control study was performed on 75 women with preterm delivery (case group) and 75 women with term delivery (control group). The research tools included a questionnaire, polymerase chain reaction (PCR) assay of cervical swab samples and ELISA assay of umbilical cord blood samples. Fisher's exact test and t test were also performed to compare qualitative variables between the two groups.
In this study, the mean age of subjects was 26.55 ± 0.53 years in the control group and 26.76 ± 0.56 years in the case group. The prevalence of in the cervical swab samples was 7 (9.33%) in the control group and 2 (2.67%) in the case group. There was no IgM antibody in either of the groups, while there was 1 (1.33%) IgG antibody in both groups.
The results of the present study showed that there was no significant relationship between infection and preterm delivery.
早产是妇产科和儿科领域的一个重要课题。其定义为每五至八分钟或更短时间出现一次规律宫缩，持续30秒。它与宫颈的渐进性变化相关，导致在妊娠22周后至37周前分娩。本研究旨在评估感染在早产女性中的作用。
本病例对照研究对75例早产女性（病例组）和75例足月分娩女性（对照组）进行。研究工具包括一份问卷、宫颈拭子样本的聚合酶链反应（PCR）检测和脐带血样本的酶联免疫吸附测定（ELISA）。还进行了费舍尔精确检验和t检验以比较两组间的定性变量。
本研究中，对照组受试者的平均年龄为26.55±0.53岁，病例组为26.76±0.56岁。对照组宫颈拭子样本中的患病率为7例（9.33%），病例组为2例（2.67%）。两组均无 IgM抗体，而两组均有1例（1.33%） IgG抗体。
本研究结果表明，感染与早产之间无显著关系。
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