Roshani Daem, Ramazanzadeh Rashid, Farhadifar Fariba, Ahmadi Amjad, Derakhshan Safoura, Rouhi Samaneh, Zarea Shamsi, Zandvakili Farnaz
Social Determinants of Health Research Center, Kurdistan University of Medical Sciences Cellular and Molecular Research Center, Kurdistan University of Medical Sciences Department of Microbiology, Faculty of Medicine, Kurdistan University of Medical Sciences Department of Obstetrics and Gynecology, Faculty of Medicine, Kurdistan University of Medical Sciences Liver and Digestive Research Center, Kurdistan University of Medical Sciences Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Medicine (Baltimore). 2018 Apr;97(16):e0335. doi: 10.1097/MD.0000000000010335.
Chlamydia trachomatis (CT) is the cause of genital tract infections in women. Some evidence has shown the role of this infection with CT in spontaneous abortions. The purpose of this study is to study the frequency of CT infection in Iranian women.
This study was performed based on PRISMA guidelines. A total of 75 articles published in Google Scholar, PubMed, ISI Web of Science, Biological abs, Iranmedex, SID, and Scopus databases were found (1986-2015) using the following keywords: CT in women, CT and Iranian women, CT and infection in Iran, CT and pregnancy in Iran, CT and preterm delivery in Iran, CT and preterm labor in Iran, CT and fertility in Iran, CT and infertility in Iran, and CT and abortion in Iran. Finally, 40 studies from different regions of Iran were included. Statistical analyses were performed using R3 and STATA 12.
From 1986 to 2015, the lowest rate of prevalence was from 2010 to 2011 (3.9%) and the highest prevalence rate was in 2009 (69.39%) in northern Iran. Fixed effects for different parts of Iran (North, South, East, and West) were Pooled proportion: 0.13 (95% confidence interval [CI] = 0.12-0.14) and for samples (cervical, vaginal, urine, and blood) the pooled proportion was = 0.14 (95% CI = 0.12-0.14).
CT infection in this study was prevalent in urine samples and the rate of CT was observed from culture methods in comparison to other methods. Because women with CT play an important role because of sexual activity for transmission and untreated women are at risk of developing sequels. Also, most studies in Iran use sensitive polymerase chain reaction tests for the detection of genital CT infections.
沙眼衣原体（CT）是女性生殖道感染的病因。一些证据表明CT感染在自然流产中所起的作用。本研究的目的是研究伊朗女性中CT感染的频率。
本研究依据PRISMA指南进行。使用以下关键词在谷歌学术、PubMed、科学引文索引（ISI）网络数据库、生物学文摘数据库、伊朗医学数据库、伊朗科学信息数据库（SID）和Scopus数据库中检索到1986年至2015年发表的共75篇文章：女性沙眼衣原体、沙眼衣原体与伊朗女性、伊朗沙眼衣原体与感染、伊朗沙眼衣原体与妊娠、伊朗沙眼衣原体与早产、伊朗沙眼衣原体与早产临产、伊朗沙眼衣原体与生育力、伊朗沙眼衣原体与不孕症、伊朗沙眼衣原体与流产。最终纳入了来自伊朗不同地区的40项研究。使用R3和STATA 12进行统计分析。
1986年至2015年，患病率最低的是2010年至2011年（3.9%），患病率最高的是2009年伊朗北部（69.39%）。伊朗不同地区（北部、南部、东部和西部）的固定效应合并比例为：0.13（95%置信区间[CI]=0.12 - 0.14），样本（宫颈、阴道、尿液和血液）的合并比例为0.14（95%CI=0.12 - 0.14）。
本研究中CT感染在尿液样本中普遍存在，与其他方法相比，通过培养法观察到CT感染率。由于感染CT的女性因性行为在传播中起重要作用，且未治疗的女性有发生后遗症的风险。此外，伊朗的大多数研究使用敏感的聚合酶链反应检测来检测生殖道CT感染。
