Yang Li, Wang Ting, Ge Mingjian, Zhang Min, Cao Youde, Guo Shuliang
Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Chongqing Medical University Chongqing China.
Department of Cardiothoracic Surgery The First Affiliated Hospital of Chongqing Medical University Chongqing China.
Respirol Case Rep. 2020 Sep 7;8(7):e00615. doi: 10.1002/rcr2.615. eCollection 2020 Oct.
Pulmonary extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) presenting as a progressive pure ground-glass nodule (GGN) coexisting with lung squamous cell carcinoma has not been reported. A 65-year-old male presented with a progressive lung GGN in the left upper lobe identified six and a half years ago but showed no symptoms. The patient had a history of tuberculosis, squamous cell carcinoma, and stomach MALT lymphoma. The patient was diagnosed with lung squamous cell carcinoma coexisting with pulmonary MALT lymphoma through computed tomography (CT)-guided lung biopsy. A progressive lung GGN presenting in a patient with squamous cell carcinoma does not always indicate multiple primary lung adenocarcinoma, especially when given a specific medical history. The development of MALT lymphoma in the lung presenting as GGNs suggests a possible association between these two entities.
表现为进行性纯磨玻璃结节（GGN）且与肺鳞状细胞癌共存的黏膜相关淋巴组织（MALT）肺结外边缘区淋巴瘤尚未见报道。一名65岁男性，6年半前发现左上叶有一个进行性肺GGN，但无症状。该患者有肺结核、鳞状细胞癌和胃MALT淋巴瘤病史。通过计算机断层扫描（CT）引导下的肺活检，该患者被诊断为肺鳞状细胞癌与肺MALT淋巴瘤共存。鳞状细胞癌患者出现进行性肺GGN并不总是提示多原发性肺腺癌，特别是在有特定病史的情况下。表现为GGN的肺MALT淋巴瘤的发生提示这两种病变之间可能存在关联。
