Bogomolets National Medical University, Kyiv 03115, Ukraine.
State Scientific Institution "Scientific-Practical Centre of Preventive and Clinical Medicine" State Administration of Affairs, Kyiv 01014, Ukraine.
Exp Oncol. 2020 Sep;42(3):242-244. doi: 10.32471/exp-oncology.2312-8852.vol-42-no-3.15029.
Metastasis of vaginal leiomyosarcoma to the thyroid gland is an extremely rare event. Here, we report a case of thyroid metastasis of vaginal leiomyosarcoma. A 65-year-old female patient presented with a multinodular toxic goiter. 5 years earlier the patient has undergone a radical vaginal resection followed by chemotherapy due to high-grade vaginal leiomyosarcoma. Fine-needle aspiration cytology of the right thyroid lobe was suggestive of the benign thyroid lesion. As the diagnosis was not clear, following a multidisciplinary team discussion the decision was made to proceed with a total thyroidectomy. Pathologic assessment of the tumor confirmed thyroid metastasis of vaginal leiomyosarcoma.
阴道平滑肌肉瘤转移至甲状腺是一种极其罕见的事件。在此，我们报告 1 例阴道平滑肌肉瘤甲状腺转移病例。1 名 65 岁女性患者因多结节毒性甲状腺肿就诊。5 年前，该患者因高级别阴道平滑肌肉瘤接受了根治性阴道切除术和化疗。右甲状腺叶细针抽吸细胞学检查提示良性甲状腺病变。由于诊断不明确，经过多学科团队讨论，决定行全甲状腺切除术。肿瘤的病理评估证实为阴道平滑肌肉瘤的甲状腺转移。
