Wang Tracy S, Ocal Idris Tolgay, Oxley Keri, Sosa Julie Ann
Section of Endocrine Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520-8062, USA.
Thyroid. 2008 Apr;18(4):425-8. doi: 10.1089/thy.2007.0276.
Primary leiomyosarcomas of the thyroid gland are rare. We present the case of a 65-year-old woman with a rapidly enlarging neck mass for 2 months. The preoperative differential diagnosis included medullary thyroid cancer, anaplastic thyroid cancer, and primary versus metastatic sarcoma. The patient underwent total thyroidectomy, bilateral central neck dissections, and cervical thymectomy; she is currently being treated with ifosfamide and adriamycin. We review the literature on leiomyosarcoma of the thyroid, including the differential diagnoses, pathology, and alternative treatment strategies, including surgery and adjuvant therapy.
甲状腺原发性平滑肌肉瘤罕见。我们报告一例65岁女性，其颈部肿块迅速增大2个月。术前鉴别诊断包括甲状腺髓样癌、未分化甲状腺癌以及原发性与转移性肉瘤。患者接受了甲状腺全切除术、双侧中央区颈部淋巴结清扫术和颈部胸腺切除术；目前正在接受异环磷酰胺和阿霉素治疗。我们回顾了关于甲状腺平滑肌肉瘤的文献，包括鉴别诊断、病理学以及包括手术和辅助治疗在内的替代治疗策略。
