Zammit M, Markey A, Webb C
ENT Department, Broadgreen Hospital, Liverpool, UK.
J Laryngol Otol. 2020 Oct 1:1-4. doi: 10.1017/S0022215120002121.
An increase in spontaneous lower motor neuron facial nerve (VIIth cranial nerve) palsies was seen during the severe acute respiratory syndrome coronavirus 2 outbreak in our emergency clinic. This led us to perform a single-centre cohort review.
A retrospective review was conducted of VIIth cranial nerve palsies from January to June 2020 and the findings were compared to those cases reviewed in the previous year. The severe acute respiratory syndrome coronavirus 2 incidence of the cohort was compared with that of the Liverpool population.
Our VIIth cranial nerve palsy incidence in the 2020 period was 3.5 per cent (30 out of 852), 2.7 higher than last year's rate of 1.3 per cent (14 out of 1081), which was a statistically significant difference (p < 0.01). Two of the 17 patients in our cohort tested positive for severe acute respiratory syndrome coronavirus 2 (11.8 per cent), contrasting with Liverpool's severe acute respiratory syndrome coronavirus 2 incidence (0.5 per cent).
Severe acute respiratory syndrome coronavirus 2 may be responsible for an increased number of facial nerve palsies; it is important for clinicians to be aware that this may being an initial presentation of the disease.
在我们的急诊诊所,严重急性呼吸综合征冠状病毒2疫情期间,自发性下运动神经元面神经(第七对颅神经)麻痹病例有所增加。这促使我们进行了一项单中心队列研究。
对2020年1月至6月的第七对颅神经麻痹病例进行回顾性研究,并将结果与前一年回顾的病例进行比较。将该队列的严重急性呼吸综合征冠状病毒2发病率与利物浦人群的发病率进行比较。
2020年期间我们的第七对颅神经麻痹发病率为3.5%(852例中有30例),比去年的1.3%(1081例中有14例)高出2.7个百分点,这在统计学上有显著差异(p<0.01)。我们队列中的17名患者中有2名严重急性呼吸综合征冠状病毒2检测呈阳性(11.8%),相比之下利物浦的严重急性呼吸综合征冠状病毒2发病率为0.5%。
严重急性呼吸综合征冠状病毒2可能导致面神经麻痹病例增多;临床医生必须意识到这可能是该疾病的初始表现。