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犬分枝杆菌引起的肉芽肿性多关节炎。

Granulomatous polyarthritis caused by in a dog.

机构信息

North Lab, Sapporo, Hokkaido, Japan.

Department of Veterinary Pathobiology, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.

出版信息

J Vet Diagn Invest. 2020 Nov;32(6):912-917. doi: 10.1177/1040638720957964. Epub 2020 Oct 1.

Abstract

A 6-y-old, 3.5-kg, spayed female Toy Poodle was presented with left forelimb lameness of 2-d duration. Two months before the initial presentation, radiography showed osteolysis of the medial epicondyle of the left humerus, and the left forelimb was amputated. Grossly, the articular villi of the elbow joint were markedly thickened, and the articular cartilage surfaces of the distal humerus and proximal radius had partial erosion. Histologically, granulomatous arthritis and osteomyelitis characterized by the presence of abundant macrophages containing numerous fungi were observed. ITS and β-tubulin sequences amplified from the isolate from the specimen were 100% and 99% identical to type strain UTHSC D16-145 of , respectively. Canine osteoarthritis caused by has not been reported previously, to our knowledge.

摘要

一只 6 岁、3.5 公斤重的已绝育雌性玩具贵宾犬出现左前肢跛行 2 天。在初次就诊前 2 个月,放射影像学显示左肱骨内上髁溶骨,左前肢被截肢。大体检查发现,肘关节的关节绒毛明显增厚,肱骨远端和桡骨近端的关节软骨表面部分被侵蚀。组织病理学观察到以大量富含真菌的巨噬细胞为特征的化脓性关节炎和骨髓炎。从标本中分离出的菌株的 ITS 和 β-微管蛋白序列与 的标准株 UTHSC D16-145 分别具有 100%和 99%的同源性。据我们所知,以前没有报道过由 引起的犬骨关节炎。

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