Goldberg Ximena, Espelt Carme, Palao Diego, Nadal Roser, Armario Antonio
Mental Health Department, Neuroscience and Mental Health Research Area, Institut d'Investigació I Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, CIBERSAM, Sabadell, Spain
Mental Health Department, Neuroscience and Mental Health Research Area, Institut d'Investigació I Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, CIBERSAM, Sabadell, Spain.
BMJ Open. 2020 Oct 1;10(10):e036561. doi: 10.1136/bmjopen-2019-036561.
Intimate partner violence (IPV) is the most common and alarming form of violence against women, affecting around 30% of all women around the world. Using an integrative methodology, we approach IPV as a form of chronic exposure to severe stress that alters the stress-response system of exposed women. The aim of this study is to test the hypothesis that sustained exposure to IPV in women confers a vulnerability-to-stress profile characterised by higher neuroendocrine and behavioural responsiveness associated with a selective attentional processing bias towards threat.
Women between 21 and 50 years old from the area of Barcelona (Spain) will be invited to participate. A sample of 82 women exposed to IPV and 41 women not exposed to IPV will be included and assessed for attentional bias and response to acute stress in a laboratory condition (the Trier Social Stress Task). The study will include quantitative and qualitative measures of cognitive performance, neuroendocrine activity and face-to-face interviews to obtain an integrative description of the stress-response profile of these women. Results are expected to help build resilience strategies with a long-lasting impression on women's healthy functioning.
The study has obtained the approval of the local Ethics Committee ('Comité de Ética de Investigación Parc Taulí de Sabadell'; 2 018 551 V.1.2 June 2018). Besides the communication of results in peer-reviewed papers and scientific congresses, the project will inform guidelines and recommendations through policy-dialogues and workshops with relevant regional and national representatives for future work and prevention strategies. Participants will be invited to be an active part in the dissemination strategy focussed on raising awareness of coping limitations and abilities that women themselves will be able to identify throughout the study.
The study has been registered at the ClinicalTrails.gov database (Identifier number: NCT03623555; Pre-results).
亲密伴侣暴力（IPV）是针对女性最常见且令人担忧的暴力形式，影响着全球约30%的女性。我们采用综合方法，将亲密伴侣暴力视为一种长期暴露于严重压力的形式，这种压力会改变受影响女性的应激反应系统。本研究的目的是检验以下假设：女性持续暴露于亲密伴侣暴力会导致一种应激易感性特征，其表现为更高的神经内分泌和行为反应性，以及对威胁的选择性注意力加工偏差。
将邀请来自西班牙巴塞罗那地区年龄在21至50岁之间的女性参与。将纳入82名遭受亲密伴侣暴力的女性和41名未遭受亲密伴侣暴力的女性样本，并在实验室条件下（特里尔社会应激测试）评估她们的注意力偏差和对急性应激的反应。该研究将包括认知表现、神经内分泌活动的定量和定性测量以及面对面访谈，以全面描述这些女性的应激反应特征。预计研究结果将有助于制定具有持久影响的恢复力策略，以促进女性的健康功能。
该研究已获得当地伦理委员会（“萨瓦德尔公园陶利研究伦理委员会”；2018年6月2日第2018551 V.1.2号）的批准。除了在同行评审论文和科学大会上交流研究结果外，该项目还将通过与相关地区和国家代表进行政策对话和举办研讨会，为未来的工作和预防策略提供指导方针和建议。将邀请参与者积极参与传播策略，重点是提高对应对局限性和能力的认识，而这些女性自身将能够在整个研究过程中识别这些应对局限性和能力。
该研究已在ClinicalTrails.gov数据库注册（标识符编号：NCT03623555；预结果）。
