Alam A N, Sarker S A, Molla A M, Rahaman M M, Greenough W B
Arch Dis Child. 1987 May;62(5):440-4. doi: 10.1136/adc.62.5.440.
A randomised three cell study was carried out in 78 children with acute diarrhoea to evaluate the relative efficacy of oral rehydration solution (ORS) made from partially hydrolysed wheat grain, cooked rice powder, or glucose. Twenty six patients with comparable age, body weight, duration of diarrhoea, and degree of dehydration were studied in each of the three groups. Initial rehydration was carried out by using intravenous Dhaka solution within one to two hours followed by administration of oral rehydration solution. The mean ORS intake during the first and second 24 hours of treatment in patients with cholera receiving wheat-ORS and rice-ORS was significantly less compared with those receiving glucose-ORS. The stool output during the same period in patients receiving wheat-ORS and rice-ORS was significantly less compared with those receiving glucose-ORS. Similar trends in both ORS intake and stool output were observed during the next 24 hours.
对78名急性腹泻儿童进行了一项随机三分组研究,以评估由部分水解小麦颗粒、熟米粉或葡萄糖制成的口服补液溶液(ORS)的相对疗效。三组中每组研究了26名年龄、体重、腹泻持续时间和脱水程度相当的患者。在1至2小时内通过静脉输注达卡溶液进行初始补液,随后给予口服补液溶液。与接受葡萄糖-ORS的患者相比,接受小麦-ORS和大米-ORS的霍乱患者在治疗的第一个和第二个24小时内的平均ORS摄入量显著减少。与接受葡萄糖-ORS的患者相比,接受小麦-ORS和大米-ORS的患者在同一时期的粪便排出量显著减少。在接下来的24小时内,ORS摄入量和粪便排出量都观察到了类似的趋势。