比较分支型视网膜静脉阻塞和正常眼压型青光眼的视盘筛板特性和视盘周围血管密度。

Comparison of lamina cribrosa properties and the peripapillary vessel density between branch retinal vein occlusion and normal-tension glaucoma.

机构信息

Department of Ophthalmology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea.

Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea.

出版信息

PLoS One. 2020 Oct 2;15(10):e0240109. doi: 10.1371/journal.pone.0240109. eCollection 2020.

DOI:10.1371/journal.pone.0240109

PMID:33007029

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7531791/

Abstract

PURPOSE

To compare the properties of the lamina cribrosa (LC) and the peripapillary vessel density between branch retinal vein occlusion (BRVO) and normal-tension glaucoma (NTG), using swept-source optical coherence tomography and optical coherence tomography angiography.

METHODS

This retrospective study included 21 eyes of 21 patients with BRVO and 43 eyes of 43 patients with NTG who were treated from June 2016 to September 2017. The anterior LC depth (ALCD) and LC thickness (LCT) at the mid-superior, central, and mid-inferior levels; the mean difference in ALCD; and the peripapillary vessel density in the superficial and deep capillary plexuses and the choriocapillaris were compared between groups.

RESULTS

ALCD at the mid-superior, central, and mid-inferior levels was significantly greater in the NTG group (P < 0.05), while LCT was comparable between the groups. The mean difference in ALCD was significantly greater in the BRVO group (P = 0.03). The peripapillary vessel density in the superotemporal segment of the superficial capillary plexus was significantly lower in the BRVO group, while the density in all segments of the choriocapillaris was significantly lower in the NTG group (P < 0.05 for all).

CONCLUSIONS

Our findings demonstrate that BRVO and NTG have different LC structures and peripapillary vessel densities.

摘要

目的

利用扫频源光学相干断层扫描和光相干断层扫描血管造影比较视网膜分支静脉阻塞（BRVO）和正常眼压性青光眼（NTG）的筛板和视盘周围血管密度的特性。

方法

本回顾性研究纳入 2016 年 6 月至 2017 年 9 月期间收治的 21 例 BRVO 患者（21 只眼）和 43 例 NTG 患者（43 只眼）。比较两组的前筛板深度（ALCD）和筛板厚度（LCT）的中上方、中央和中下方水平，ALCD 的平均差值，以及浅层和深层毛细血管丛及脉络膜毛细血管的视盘周围血管密度。

结果

NTG 组的 ALCD 在中上方、中央和中下方水平显著较大（P < 0.05），而两组的 LCT 无显著差异。BRVO 组的 ALCD 平均差值显著较大（P = 0.03）。BRVO 组浅层毛细血管丛的上颞段视盘周围血管密度显著较低，而 NTG 组脉络膜毛细血管各段的密度均显著较低（所有 P < 0.05）。