Baek Jiwon, Jeon Soo-Ji, Kim Jin-Ho, Park Chan-Kee, Park Hae-Young L
Department of Ophthalmology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon 14647, Korea.
Department of Ophthalmology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Korea.
J Clin Med. 2021 Jun 10;10(12):2574. doi: 10.3390/jcm10122574.
We analyzed the vascular densities (VDs) of the optic disc areas in eyes with normal-tension glaucoma (NTG) according to their branch retinal vessel occlusion (BRVO) status. The VDs of the optic discs and peripapillary areas of 68 NTG patients with BRVO (BRVO group; BRVO eyes and fellow eyes) and 37 patients with NTG alone (control eyes) were measured on angiographic images obtained via swept-source optical coherence tomography angiography. VDs were compared among groups and correlations were assessed. The VD of the optic disc large vessel was the highest in BRVO eyes, followed by the fellow eyes and controls (all < 0.05). Conversely, small and medium vessel VD was in the opposite order (all < 0.05). Large vessel VD was negatively correlated with small and medium vessel VD (r = -0.697, < 0.001). Peripapillary VD was lower in the BRVO eyes than in the control and fellow eyes ( < 0.001 and = 0.861, respectively). In conclusion, significant changes in the distribution of VDs for optic disc larger vessel and small and medium vessels were observed in both eyes of NTG patients with BRVO, compared to NTG patients without BRVO.
我们根据视网膜分支血管阻塞（BRVO）状态，分析了正常眼压性青光眼（NTG）患者视盘区域的血管密度（VDs）。通过扫频光学相干断层扫描血管造影获得的血管造影图像，测量了68例患有BRVO的NTG患者（BRVO组；BRVO眼和对侧眼）和37例单纯NTG患者（对照眼）的视盘和视乳头周围区域的VDs。比较了各组之间的VDs，并评估了相关性。视盘大血管的VD在BRVO眼中最高，其次是对侧眼和对照眼（均P<0.05）。相反，中小血管VD的顺序则相反（均P<0.05）。大血管VD与中小血管VD呈负相关（r=-0.697，P<0.001）。BRVO眼的视乳头周围VD低于对照眼和对侧眼（分别为P<0.001和P=0.861）。总之，与无BRVO的NTG患者相比，患有BRVO的NTG患者双眼视盘大血管以及中小血管的VD分布均有显著变化。
