Department of Nutrition and Health Education, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Int J Environ Res Public Health. 2020 Sep 30;17(19):7171. doi: 10.3390/ijerph17197171.
The prevalence of metabolic diseases has increased over the past few decades, and epidemiological studies suggest that metabolic diseases may be associated with lifestyle. The purpose of the present study was to investigate the relationship between leisure-time sedentary behaviors (LTSBs) and metabolic risks in middle-aged women in China. Data came from the China National Nutrition and Health Surveillance (CNNHS) in 2010-2012. A total of 2643 women aged 46 to 53 years were involved. Multiple linear regression was used to examine the association of leisure-time sedentary duration (LTSD) with total cholesterol (TC), triglyceride (TG), waist circumference (WC), and body mass index (BMI). Restrictive cubic splines (RCS) were used to plot the curves between LTSD and the risk of metabolic diseases. Region, education, income, alcohol consumption, exercise, daily energy intake, and fat energy ratio were adjusted for all models. After adjusting for potential influencing factors, the results of multiple linear regression showed that for each additional hour increase in LTSD, TC and TG increased by 0.03 mmol/L and 0.04 mmol/L, respectively. The results of RCS curves showed that the risks of MetS ( for trend = 0.0276), obesity ( for trend = 0.0369), hypertension ( for trend = 0.0062), and hypercholesteremia ( for trend = 0.0033) increased with the increase in LTSD. LTSB was associated with the risks of MetS, obesity, hypertension, and hypercholesteremia in middle-aged women. Reducing LTSD may be an effective way of preventing metabolic diseases in middle-aged women.
过去几十年中，代谢疾病的患病率不断上升，流行病学研究表明代谢疾病可能与生活方式有关。本研究旨在探讨中国中年女性休闲时间久坐行为（LTSB）与代谢风险之间的关系。数据来自 2010-2012 年中国国家营养与健康监测（CNNHS）。共纳入 2643 名 46-53 岁的女性。采用多元线性回归分析休闲时间久坐时间（LTSD）与总胆固醇（TC）、甘油三酯（TG）、腰围（WC）和体重指数（BMI）的关系。采用限制性三次样条（RCS）绘制 LTSD 与代谢疾病风险的曲线。所有模型均调整了区域、教育程度、收入、饮酒、运动、每日能量摄入和脂肪能量比。在调整潜在影响因素后，多元线性回归的结果表明，LTSD 每增加 1 小时，TC 和 TG 分别增加 0.03mmol/L 和 0.04mmol/L。RCS 曲线的结果表明，代谢综合征（ for trend = 0.0276）、肥胖（ for trend = 0.0369）、高血压（ for trend = 0.0062）和高胆固醇血症（ for trend = 0.0033）的患病风险随 LTSD 的增加而增加。LTSB 与中年女性代谢综合征、肥胖、高血压和高胆固醇血症的患病风险相关。减少 LTSD 可能是预防中年女性代谢疾病的有效方法。
