Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.
Metab Syndr Relat Disord. 2009 Dec;7(6):529-36. doi: 10.1089/met.2009.0023.
This study examines leisure time sedentary behavior (LTSB) and usual occupational/domestic activity (UODA) and their relationship with metabolic syndrome and individual cardiovascular disease (CVD) risk factors, independent of physical activity level.
National Health and Nutrition Examination Survey (NHANES) 2003-2006 data from men (n = 1868) and women (n = 1688) with fasting measures were classified as having metabolic syndrome by the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) definition. LTSB was determined from self-reported television viewing and computer usage. UODA was self-reported daily behavior (sitting, standing, walking, carrying loads).
LTSB >or=4 hours/day was associated with odds of having metabolic syndrome of 1.94 (95% confidence interval [CI], 1.24, 3.03) in men compared to <or=1 hour/day. LTSB >or=4 hour/day was also associated with higher odds of elevated waist circumference (1.88, CI, 1.03, 3.41), low high-density lipoprotein cholesterol (HDL-C) (1.84, CI, 1.35, 2.51), and high blood pressure (1.55, CI, 1.07, 2.24) in men. LTSB 2-3 hours/day was associated with higher odds of elevated glucose (1.32, CI, 1.00, 1.75) in men. In women, odds of metabolic syndrome were 1.54 (CI, 1.00, 2.37) with >or=4 hours/day LTSB, but LTSB was not associated with risk of the individual CVD risk factors. Higher LTSB was associated with metabolic syndrome in inactive men (1.50, CI, 1.07, 2.09), active men (1.74, CI, 1.11, 2.71), inactive women (1.69, CI, 1.24, 2.33), but not active women (1.62, CI, 0.87,3.01). UODA was not strongly associated with metabolic syndrome or CVD risk factors in either men or women.
In men, high LTSB is associated with higher odds of metabolic syndrome and individual CVD risk factors regardless of meeting physical activity recommendations. In women, high LTSB is associated with higher odds of metabolic syndrome only in those not meeting the physical activity recommendations.
本研究旨在探讨闲暇时间久坐行为（LTSB）和日常职业/家务活动（UODA）与代谢综合征及个体心血管疾病（CVD）风险因素的关系，而不考虑身体活动水平。
利用 2003-2006 年美国国家健康和营养调查（NHANES）中接受禁食测量的男性（n=1868）和女性（n=1688）的数据，采用美国心脏协会/美国国立心肺血液研究所（AHA/NHLBI）的定义，将代谢综合征分为代谢综合征。LTSB 是通过自我报告的看电视和使用电脑来确定的。UODA 是通过自我报告的日常行为（坐、站、走、负重）来确定的。
与每天<1 小时的男性相比，每天久坐时间>或=4 小时的男性发生代谢综合征的几率为 1.94（95%置信区间[CI]，1.24，3.03）。每天久坐时间>或=4 小时的男性还与腰围增大（1.88，CI，1.03，3.41）、高密度脂蛋白胆固醇（HDL-C）降低（1.84，CI，1.35，2.51）和高血压（1.55，CI，1.07，2.24）的风险增加有关。对于男性，每天 2-3 小时的 LTSB 与升高的血糖（1.32，CI，1.00，1.75）有关。在女性中，每天久坐时间>或=4 小时与代谢综合征的几率为 1.54（CI，1.00，2.37），但 LTSB 与个体 CVD 风险因素无关。在不活跃的男性（1.50，CI，1.07，2.09）、活跃的男性（1.74，CI，1.11，2.71）、不活跃的女性（1.69，CI，1.24，2.33）中，较高的 LTSB 与代谢综合征相关，但在活跃的女性（1.62，CI，0.87，3.01）中则不然。无论男女，UODA 与代谢综合征或 CVD 风险因素均无明显相关性。
在男性中，无论是否符合身体活动建议，久坐时间较长均与代谢综合征和个体 CVD 风险因素的几率增加有关。在女性中，只有不符合身体活动建议的女性，久坐时间较长才与代谢综合征的几率增加有关。
