Department of Clinical and Experimental Medicine, University of Pisa, Via Roma, 67, 56100, Pisa, Italy.
Department of Obstetrics and Gynecology, University Hospital, Basel, Switzerland.
Maturitas. 2021 Jan;143:223-230. doi: 10.1016/j.maturitas.2020.09.005. Epub 2020 Sep 30.
The prevalence of urinary incontinence and of other lower urinary tract symptoms increases after the menopause and affects between 38 % and 55 % of women aged over 60 years. While urinary incontinence has a profound impact on quality of life, few affected women seek care.
The aim of this clinical guide is to provide an evidence-based approach to the management of urinary incontinence in postmenopausal women.
Literature review and consensus of expert opinion.
Healthcare professionals should consider urinary incontinence a clinical priority and develop appropriate diagnostic skills. They should be able to identify and manage any relevant modifiable factors that could alleviate the condition. A wide range of treatment options is available. First-line management includes lifestyle and behavioral modification, pelvic floor exercises and bladder training. Estrogens and other pharmacological interventions are helpful in the treatment of urgency incontinence that does not respond to conservative measures. Third-line therapies (e.g. sacral neuromodulation, intravesical onabotulinum toxin-A injections and posterior tibial nerve stimulation) are useful in selected patients with refractory urge incontinence. Surgery should be considered in postmenopausal women with stress incontinence. Midurethral slings, including retropubic and transobturator approaches, are safe and effective and should be offered.
尿失禁和其他下尿路症状在绝经后更为常见,影响 60 岁以上女性的 38%至 55%。虽然尿失禁对生活质量有重大影响,但很少有受影响的女性寻求治疗。
本临床指南旨在为绝经后女性尿失禁的管理提供循证方法。
文献回顾和专家意见共识。
医疗保健专业人员应将尿失禁视为临床重点,并培养适当的诊断技能。他们应该能够识别和管理任何可能缓解病情的相关可改变因素。有多种治疗选择。一线治疗包括生活方式和行为改变、骨盆底运动和膀胱训练。雌激素和其他药物干预措施有助于治疗对保守措施无反应的急迫性尿失禁。三线治疗(如骶神经调节、膀胱内注射肉毒毒素 A 和胫后神经刺激)对有难治性急迫性尿失禁的特定患者有用。对于压力性尿失禁的绝经后女性,应考虑手术。包括经耻骨后和经闭孔途径的尿道中段吊带术是安全有效的,应予以提供。