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COVID-19 与 34 周妊娠伴严重特征的子痫前期。

COVID-19 and preeclampsia with severe features at 34-weeks gestation.

机构信息

Department of Emergency Medicine, Maine Medical Center, 22 Bramhall Street, Portland, ME 04102, United States of America.

Southern Maine Healthcare, Department of Emergency Medicine, Tufts University School of Medicine, 1 Medical Center Drive, Biddeford, ME 04005, United States of America.

出版信息

Am J Emerg Med. 2021 Jan;39:252.e3-252.e5. doi: 10.1016/j.ajem.2020.06.052. Epub 2020 Jun 25.

Abstract

The evolving coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a rapid expansion of knowledge on the disease's clinical manifestations, laboratory and radiographic abnormalities, and patient trajectories. One area of particular focus is the effect that this illness may have on pregnancy and maternal-fetal disease. As of April 24, 2020, we identified 55 English language reports in the scientific literature summarizing data for 339 women and 258 fetuses and neonates. The majority of these data have focused on maternal-fetal transmission and neonatal outcomes. One systematic review and meta-analysis including the spectrum of coronaviruses [Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and COVID-19] in pregnancy noted increased rates of adverse outcomes associated with this group of infections. Here, we report the case of a COVID-19 positive woman presenting to our emergency department (ED) at 34 weeks gestation with preeclampsia. This case highlights the unique diagnostic and therapeutic challenges associated with treating patients with these concomitant diseases.

摘要

不断演变的 2019 年冠状病毒病(COVID-19)大流行是由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的,这导致人们对该病的临床表现、实验室和影像学异常以及患者病程迅速扩展了认识。其中一个特别关注的领域是这种疾病可能对妊娠和母婴疾病的影响。截至 2020 年 4 月 24 日,我们在科学文献中发现了 55 篇英文报告,这些报告汇总了 339 名妇女和 258 名胎儿和新生儿的数据。这些数据主要集中在母婴传播和新生儿结局上。一项包括 SARS、MERS 和 COVID-19 在内的冠状病毒妊娠谱的系统评价和荟萃分析指出,与这组感染相关的不良结局发生率增加。在这里,我们报告了一例 COVID-19 阳性妇女在 34 周妊娠时因子痫前期到我们的急诊就诊的病例。该病例突出了与治疗这些合并疾病相关的独特诊断和治疗挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a23/7315969/77befba17c19/gr1_lrg.jpg

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