Division of Infectious Diseases, Cleveland Clinic Akron General, Akron, OH, USA; Department of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.
Medical Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA; Case VA Center for Antimicrobial Resistance and Epidemiology (Case VA-CARES), Case Western Reserve University, Cleveland, OH, USA.
Infect Dis Clin North Am. 2020 Dec;34(4):649-658. doi: 10.1016/j.idc.2020.04.002. Epub 2020 Sep 30.
The effectiveness of antibiotics continues to erode because of the relentless spread of antimicrobial resistance (AMR). Public and private foundations, professional organizations, and international health agencies recognize the threat posed by AMR and have issued calls for action. One of the main drivers of AMR is overprescription of antibiotics, both in human and in veterinary medicine. The One Health concept is a response from a broad group of stakeholders to counter the global health threat posed by AMR. In this article, we discuss current trends in AMR and suggest strategies to mitigate its ongoing dissemination.
由于抗菌药物耐药性（AMR）的无情传播，抗生素的有效性不断受到侵蚀。公共和私人基金会、专业组织和国际卫生机构都认识到 AMR 带来的威胁，并发出了行动呼吁。导致 AMR 的主要因素之一是抗生素的过度处方，无论是在人类医学还是兽医医学中。“同一健康”理念是广大利益攸关方为应对 AMR 这一全球健康威胁而做出的回应。在本文中，我们讨论了 AMR 的当前趋势，并提出了减轻其持续传播的策略。
