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人类肠道微生物群既不是器官也不是共生体。

The human gut microbiota is neither an organ nor a commensal.

机构信息

Department of Sciences, University of Basilicata, Potenza, Italy.

出版信息

FEBS Lett. 2020 Oct;594(20):3262-3271. doi: 10.1002/1873-3468.13946. Epub 2020 Oct 19.

Abstract

The recent explosive increase in the number of works on gut microbiota has been accompanied by the spread of rather vague or improper definitions, chosen more for common use than for experimental evidence. Among them are those defining the human gut microbiota as an organ of our body or as a commensal. But, is the human gut microbiota an organ or a commensal? Here, we address this issue to spearhead a reflection on the real roles of the human gut microbiota in our life. Actually, the misuse of the vocabulary used to describe the properties and functions of the gut microbiota may generate confusion and cause misunderstandings both in the scientific community and among the general public.

摘要

最近,关于肠道微生物组的研究数量呈爆炸式增长,同时也出现了相当模糊或不恰当的定义,这些定义更多的是基于常见用法,而不是基于实验证据。其中包括将人类肠道微生物组定义为我们身体的一个器官或共生体。但是,人类肠道微生物组到底是一个器官还是共生体呢?在这里,我们提出这个问题,旨在引发人们对人类肠道微生物组在我们生活中的真正作用的思考。实际上,对描述肠道微生物组特性和功能的词汇的滥用可能会在科学界和公众中造成混淆和误解。

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