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是否存在血管方面的情况?意大利伦巴第大区新冠疫情期间的血管相关后果。

Is there a vascular side of the story? Vascular consequences during COVID-19 outbreak in Lombardy, Italy.

作者信息

Bissacco Daniele, Grassi Viviana, Lomazzi Chiara, Domanin Maurizio, Bellosta Raffaello, Piffaretti Gabriele, Trimarchi Santi

机构信息

Vascular Surgery Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Department of Clinical and Community Sciences, University of Milan, Milan, Italy.

出版信息

J Card Surg. 2021 May;36(5):1677-1682. doi: 10.1111/jocs.15069. Epub 2020 Oct 4.

DOI:10.1111/jocs.15069
PMID:33012015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7675479/
Abstract

BACKGROUND

Lombardy, in the northern Italy, was one of the most affected region in the world by novel coronavirus COVID-19 outbreak. Due to the dramatic amount of confirmed positive cases and deaths, all clinical and surgical hospital departments changed their daily activities to face emergent pandemic situations. In particular, vascular surgery units reorganized their role and priorities for both elective and urgent patients requiring open or endovascular interventions.

MATERIAL & METHODS: This brief review summarizes organization of vascular Lombardy centers network adopted during pandemic period and clinical evidences published so far by regional referral and nonreferral hospitals in terms of vascular surgery and medicine implications in COVID-19 positive or negative patients managements.

RESULTS

Different patterns of disease were described during phase 1 COVID-19 outbreak in Lombardy region, with major attention in pheriperal artery disease and venous thrombosis.

CONCLUSION

COVID-19 infection seems to be not only a pulmonary but also a vascular (arterial and venous) disease. Further study are necessary to described mid and long-term outcomes in COVID-19 vascular patients population.

摘要

背景

意大利北部的伦巴第是全球受新型冠状病毒COVID-19疫情影响最严重的地区之一。由于确诊阳性病例和死亡人数众多,所有临床和外科医院科室都改变了日常活动,以应对紧急的大流行情况。特别是,血管外科单位重新调整了对需要开放或血管内干预的择期和急诊患者的作用和优先级。

材料与方法

本简要综述总结了大流行期间伦巴第血管中心网络的组织情况,以及该地区转诊和非转诊医院迄今发表的关于COVID-19阳性或阴性患者管理中血管外科和医学影响的临床证据。

结果

在伦巴第地区COVID-19疫情的第一阶段描述了不同的疾病模式,主要关注外周动脉疾病和静脉血栓形成。

结论

COVID-19感染似乎不仅是一种肺部疾病,也是一种血管(动脉和静脉)疾病。有必要进一步研究以描述COVID-19血管患者群体的中长期结果。

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本文引用的文献

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Ann Vasc Surg. 2020 Nov;69:89. doi: 10.1016/j.avsg.2020.07.016. Epub 2020 Jul 28.
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Eur J Cardiothorac Surg. 2020 Aug 1;58(2):319-327. doi: 10.1093/ejcts/ezaa204.
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The outlook for diagnostic purposes of the 2019-novel coronavirus disease.新型冠状病毒病的诊断展望。
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Coronavirus Disease-2019 (COVID-19) and Cardiovascular Complications.新型冠状病毒病 2019(COVID-19)与心血管并发症。
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Covid-19 and thrombosis: what do we know about the risks and treatment?新冠病毒与血栓形成:我们对风险和治疗了解多少?
BMJ. 2020 May 21;369:m2058. doi: 10.1136/bmj.m2058.
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Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.新型冠状病毒肺炎的肺血管内皮细胞炎症、血栓形成和血管生成。
N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.
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