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一名新冠肺炎年轻男性患者出现意外动脉血栓形成和急性肢体缺血:病例报告

Unexpected arterial thrombosis and acute limb ischemia in a young male patient with COVID-19: A case report.

作者信息

Aljabri Badr, Aldossary Mohammed Yousef

机构信息

Division of Vascular Surgery, Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Division of Vascular Surgery, Department of Surgery, Dammam Medical Complex, Dammam, Saudi Arabia.

出版信息

Front Surg. 2023 Jan 30;10:1092287. doi: 10.3389/fsurg.2023.1092287. eCollection 2023.

Abstract

INTRODUCTION

The spread of severe acute respiratory syndrome coronavirus 2 has resulted in coronavirus disease 2019 (COVID-19) pandemic, raising significant concerns. COVID-19 can lead to thrombotic complications such as acute limb ischemia (ALI). In patients with COVID-19, thrombotic complications may increase the risk of morbidity and mortality.

PRESENTATION OF CASE

We report the case of a 37-year-old man who presented with a 2 weeks history of right foot pain, toes blackish discoloration, and numbness. He tested positive for COVID-19 10 days prior to his presentation. Computed tomography angiography (CTA) of the lower limbs revealed near-complete occlusion of the right popliteal artery with single-vessel posterior tibial artery runoff. The patient was brought to a hybrid operating room, and diagnostic angiography confirmed the diagnosis. He underwent popliteal artery thromboembolectomy and intraoperative thrombolysis through a posterior approach. A completion angiography demonstrated a patent popliteal artery with a 2-vessels patency to the foot. His postoperative recovery was uneventful. After surgery, the popliteal, anterior tibial, and posterior tibial arteries were all palpable. The patient was discharged home on antiplatelet therapy with frequent postoperative follow-ups during the last 1 year in our outpatient clinic.

DISCUSSION

The frequency of ALI has reduced worldwide, and the hypercoagulable condition remains an infrequent cause of limb ischemia. Patients with COVID-19 have a 35%-45% thromboembolic complication rate. In many studies, the virus launches a second attack between 7 and 14 days after symptom onset, possibly causing hypercoagulability. If conservative treatment fails, various surgical methods, including thromboembolectomy, thrombolysis, and thrombosuction, can be performed to treat ALI.

CONCLUSION

In mild ALI symptoms, unfractionated heparin can be used with vigilant follow-up. Open and endovascular procedures are currently used to treat patients with acute limb ischemia, and technological advancements continue to make interventions easier and safer.

摘要

引言

严重急性呼吸综合征冠状病毒2的传播导致了2019冠状病毒病(COVID-19)大流行,引发了重大关注。COVID-19可导致血栓形成并发症,如急性肢体缺血(ALI)。在COVID-19患者中,血栓形成并发症可能会增加发病和死亡风险。

病例介绍

我们报告一例37岁男性病例,该患者有2周的右足疼痛、脚趾发黑和麻木病史。他在就诊前10天COVID-19检测呈阳性。下肢计算机断层扫描血管造影(CTA)显示右腘动脉几乎完全闭塞,仅单支胫后动脉有血流。患者被送往杂交手术室,诊断性血管造影确诊了病情。他接受了腘动脉血栓切除术,并通过后路进行了术中溶栓。血管造影复查显示腘动脉通畅,足部两支血管通畅。他术后恢复顺利。术后,腘动脉、胫前动脉和胫后动脉均可触及。患者出院时接受抗血小板治疗,在过去一年中,我们的门诊对其进行了频繁的术后随访。

讨论

ALI的发生率在全球范围内有所下降,高凝状态仍然是肢体缺血的罕见原因。COVID-19患者的血栓栓塞并发症发生率为35%-45%。在许多研究中,病毒在症状出现后7至14天会再次攻击,可能导致高凝状态。如果保守治疗失败,可以采用包括血栓切除术、溶栓和血栓抽吸术在内的各种手术方法来治疗ALI。

结论

在轻度ALI症状中,可使用普通肝素并进行密切随访。目前,开放手术和血管内手术用于治疗急性肢体缺血患者,技术进步继续使干预变得更容易、更安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef72/9927001/3a383119d847/fsurg-10-1092287-g001.jpg

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