Queensland University of Technology (QUT), Centre for Vision and Eye Research, School of Optometry and Vision Science, Contact Lens and Visual Optics Laboratory, Queensland, Australia.
Queensland University of Technology (QUT), Centre for Vision and Eye Research, School of Optometry and Vision Science, Contact Lens and Visual Optics Laboratory, Queensland, Australia.
Cont Lens Anterior Eye. 2021 Feb;44(1):115-119. doi: 10.1016/j.clae.2020.09.001. Epub 2020 Oct 2.
To investigate the incidence and peak elevation of conjunctival prolapse during short-term open eye scleral lens wear and its association with lens fitting characteristics.
Ten young, healthy adults (mean age ± SD, 30 ± 4 years) wore a high Dk sealed scleral lens for 90 min with an initial central post-lens fluid reservoir thickness defined as low (144 ± 23 μm), medium (487 ± 63 μm), and high (726 ± 55 μm). Optical coherence tomography was used to quantify limbal clearance, lens settling, and changes in conjunctival thickness.
The incidence of conjunctival prolapse was 37% across all fluid reservoir thickness conditions, with 80% of participants exhibiting conjunctival prolapse at least once. Prolapse was observed more frequently nasally (73%) than temporally (27%) (p < 0.01). The peak prolapse elevation did not vary with fluid reservoir thickness condition or anatomical location (both p > 0.05). For the low fluid reservoir thickness condition, eyes with conjunctival prolapse had greater initial limbal clearance (97 ± 38 μm compared to 43 ± 34 μm, p = 0.01) and more settling after 90 min of lens wear (-85 ± 30 μm compared to -34 ± 29 μm, p < 0.01). Greater limbal settling was associated with a higher peak elevation of the conjunctival prolapse (r = 0.48, p = 0.02), but not with landing zone tissue compression (r = 0.22, p = 0.33) or the initial or final limbal fluid reservoir thickness asymmetry (r ≤ 0.07, p > 0.05).
Conjunctival prolapse was commonly observed during short-term sealed scleral lens wear in healthy eyes. The peak elevation of the conjunctival prolapse was associated with the extent of limbal settling, but not landing zone tissue compression or fluid reservoir thickness asymmetry.
研究短期开放式巩膜镜佩戴过程中瞬目时结膜膨出的发生率和峰值，并探讨其与镜片适配特征的关系。
10 名年轻健康的成年人（平均年龄 ± 标准差，30 ± 4 岁）佩戴高透氧系数（Dk）密封式巩膜镜 90 分钟，初始中央后泪液储留区厚度分别设定为低（144 ± 23 μm）、中（487 ± 63 μm）、高（726 ± 55 μm）三组。应用光学相干断层扫描技术定量评估角巩膜缘间隙、镜片下沉以及结膜厚度的变化。
在所有储留区厚度条件下，结膜膨出的发生率为 37%，80%的参与者至少发生过一次结膜膨出。鼻侧（73%）比颞侧（27%）更易发生结膜膨出（p < 0.01）。结膜膨出的峰值高度与储留区厚度条件或解剖位置无关（均 p > 0.05）。对于低储留区厚度条件，发生结膜膨出的眼初始角巩膜缘间隙更大（97 ± 38 μm 比 43 ± 34 μm，p = 0.01），佩戴 90 分钟后镜片下沉更多（-85 ± 30 μm 比 -34 ± 29 μm，p < 0.01）。更大的角巩膜缘下沉与结膜膨出的峰值高度升高相关（r = 0.48，p = 0.02），但与着陆区组织压缩（r = 0.22，p = 0.33）或初始或最终角巩膜缘储留区厚度不对称性（r ≤ 0.07，p > 0.05）无关。
在健康眼短期佩戴密封式巩膜镜期间，常观察到结膜膨出。结膜膨出的峰值高度与角巩膜缘下沉程度相关，与着陆区组织压缩或储留区厚度不对称性无关。
