• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

个人护理产品配方对严重急性呼吸综合征冠状病毒 2 的抗病毒功效。

Antiviral efficacy of personal care formulations against Severe Acute Respiratory Syndrome Coronavirus 2.

机构信息

Unilever Research and Development Centre, 64 Main Road, Whitefield, Bengaluru, Karnataka 560066, India.

Unilever Research and Development, 45 Commerce Drive, Trumbull, CT 06611, USA.

出版信息

Infect Dis Health. 2021 Feb;26(1):63-66. doi: 10.1016/j.idh.2020.09.003. Epub 2020 Sep 17.

DOI:10.1016/j.idh.2020.09.003
PMID:33012695
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7498208/
Abstract

BACKGROUND

Non-therapeutic interventions such as practicing good hand hygiene continue to be the mainstay of protection from SARS-CoV-2 and other emerging respiratory viruses.

METHODS

We have evaluated a range of commercially available personal care products including soaps, handwash liquids and alcohol-based hand sanitizers for antiviral efficacy against a clinical isolate of SARS-CoV-2 using internationally accepted standardized protocols at user-relevant contact time-points and product dilutions.

RESULTS

All the tested products resulted in 3 to 4 log reduction of SARS-CoV-2 titer.

CONCLUSION

Our data re-affirms recommendations by global public health authorities that proper hand hygiene can reduce SARS-CoV-2 viral load significantly which should likely limit spread of the contagion.

摘要

背景

非治疗性干预措施,如保持良好的手部卫生,仍然是预防 SARS-CoV-2 和其他新兴呼吸道病毒的主要手段。

方法

我们评估了一系列市售的个人护理产品,包括肥皂、洗手液和酒精基洗手液,使用国际公认的标准化方案,在用户相关的接触时间点和产品稀释度下,针对 SARS-CoV-2 的临床分离株评估其抗病毒功效。

结果

所有测试的产品均使 SARS-CoV-2 滴度降低了 3 到 4 个对数级。

结论

我们的数据再次证实了全球公共卫生当局的建议,即正确的手部卫生可以显著降低 SARS-CoV-2 的病毒载量,从而可能限制传染的传播。

相似文献

1
Antiviral efficacy of personal care formulations against Severe Acute Respiratory Syndrome Coronavirus 2.个人护理产品配方对严重急性呼吸综合征冠状病毒 2 的抗病毒功效。
Infect Dis Health. 2021 Feb;26(1):63-66. doi: 10.1016/j.idh.2020.09.003. Epub 2020 Sep 17.
2
Inactivation of SARS-CoV-2 by commercially available alcohol-based hand sanitizers.商业用酒精类手部消毒剂对 SARS-CoV-2 的灭活作用。
Am J Infect Control. 2021 Mar;49(3):401-402. doi: 10.1016/j.ajic.2020.08.020. Epub 2020 Aug 18.
3
Evaluating the Antimicrobial Properties of Commercial Hand Sanitizers.评估市售手部消毒剂的抗菌性能。
mSphere. 2021 Mar 3;6(2):e00062-21. doi: 10.1128/mSphere.00062-21.
4
Hand hygiene in preventing COVID-19 transmission.手部卫生在预防新冠病毒传播中的作用
Cutis. 2020 May;105(5):233-234.
5
Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols.世卫组织推荐的手部消毒剂配方和醇类对严重急性呼吸综合征冠状病毒 2 的灭活作用。
Emerg Infect Dis. 2020 Jul;26(7):1592-1595. doi: 10.3201/eid2607.200915. Epub 2020 Jun 21.
6
Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2.不含酒精的手部消毒剂和其他季铵盐消毒剂可快速、有效地使 SARS-CoV-2 失活。
J Hosp Infect. 2021 Feb;108:142-145. doi: 10.1016/j.jhin.2020.11.023. Epub 2020 Nov 28.
7
Synergistic effects of anionic surfactants on coronavirus (SARS-CoV-2) virucidal efficiency of sanitizing fluids to fight COVID-19.阴离子表面活性剂对消毒液杀新冠病毒(SARS-CoV-2)效率的协同作用。
Food Chem Toxicol. 2020 Nov;145:111702. doi: 10.1016/j.fct.2020.111702. Epub 2020 Aug 26.
8
Amuchina Gel Xgerm hand rub virucidal activity against SARS-CoV-2.Amuchina Gel Xgerm 手部免洗液对 SARS-CoV-2 具有病毒杀灭活性。
Future Microbiol. 2021 Jul;16(11):797-800. doi: 10.2217/fmb-2021-0128. Epub 2021 Jun 24.
9
Hand sanitizers: A review of ingredients, mechanisms of action, modes of delivery, and efficacy against coronaviruses.手部消毒剂:成分、作用机制、输送方式和抗冠状病毒效果综述。
Am J Infect Control. 2020 Sep;48(9):1062-1067. doi: 10.1016/j.ajic.2020.06.182. Epub 2020 Jun 18.
10
Inactivation of SARS-CoV-2 by Ozonated Glycerol.臭氧甘油对 SARS-CoV-2 的灭活作用。
Food Environ Virol. 2021 Sep;13(3):316-321. doi: 10.1007/s12560-021-09485-x. Epub 2021 Jun 26.

引用本文的文献

1
Development of a pseudo-typed virus particle based method to determine the efficacy of virucidal agents.一种基于假型病毒颗粒的方法用于确定杀病毒剂的功效的开发。
Sci Rep. 2024 Jan 25;14(1):2174. doi: 10.1038/s41598-024-52177-2.
2
Efficacy of a New Alcohol-Free Organic Acid-Based Hand Sanitizer against Foodborne Pathogens.一种新型无酒精有机酸基洗手液对食源性病原体的功效
Toxics. 2023 Nov 17;11(11):938. doi: 10.3390/toxics11110938.
3
Personal care formulations demonstrate virucidal efficacy against multiple SARS-CoV-2 variants of concern: Implications for hand hygiene and public health.个人护理配方对多种值得关注的新冠病毒变异株显示出杀病毒效果:对手部卫生和公共卫生的意义。
PLOS Glob Public Health. 2022 Feb 24;2(2):e0000228. doi: 10.1371/journal.pgph.0000228. eCollection 2022.
4
Study of Cationic Surfactants Raw Materials for COVID-19 Disinfecting Formulations by Potentiometric Surfactant Sensor.基于电位型表面活性剂传感器对用于 COVID-19 消毒剂配方的阳离子表面活性剂原料的研究。
Sensors (Basel). 2023 Feb 13;23(4):2126. doi: 10.3390/s23042126.
5
Evaluation of Environmental Stability and Disinfectant Effectiveness for Human Coronavirus OC43 on Human Skin Surface.人冠状病毒OC43在人体皮肤表面的环境稳定性及消毒剂有效性评估
Microbiol Spectr. 2023 Feb 22;11(2):e0238122. doi: 10.1128/spectrum.02381-22.
6
Skin care and hygiene among healthcare professionals during and after the SARS-CoV-2 pandemic.2019冠状病毒病大流行期间及之后医护人员的皮肤护理与卫生
SAGE Open Med. 2021 Dec 8;9:20503121211062795. doi: 10.1177/20503121211062795. eCollection 2021.
7
Evaluating the virucidal activity of four disinfectants against SARS-CoV-2.评估四种消毒剂对 SARS-CoV-2 的病毒杀灭活性。
Am J Infect Control. 2022 Mar;50(3):319-324. doi: 10.1016/j.ajic.2021.10.035. Epub 2021 Nov 12.
8
Disinfection methods against SARS-CoV-2: a systematic review.针对 SARS-CoV-2 的消毒方法:系统评价。
J Hosp Infect. 2022 Jan;119:84-117. doi: 10.1016/j.jhin.2021.07.014. Epub 2021 Oct 18.
9
Soap, water, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): an ancient handwashing strategy for preventing dissemination of a novel virus.肥皂、水与严重急性呼吸综合征冠状病毒2(SARS-CoV-2):一种预防新型病毒传播的古老洗手策略。
PeerJ. 2021 Sep 17;9:e12041. doi: 10.7717/peerj.12041. eCollection 2021.
10
Developments in Nano-materials and Analysing its role in Fighting COVID-19.纳米材料的发展及其在抗击新冠肺炎中的作用分析
Mater Today Proc. 2021;47:4357-4363. doi: 10.1016/j.matpr.2021.05.020. Epub 2021 May 9.