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颈椎脊髓损伤后功能重建的不同刺激方法综述及呼吸功能比较

A Review of Different Stimulation Methods for Functional Reconstruction and Comparison of Respiratory Function after Cervical Spinal Cord Injury.

作者信息

Chang Jiaqi, Shen Dongkai, Wang Yixuan, Wang Na, Liang Ya

机构信息

School of Automation Science and Electrical Engineering, Beihang University, Beijing 100191, China.

Engineering Training Cent, Beihang University, Beijing 100191, China.

出版信息

Appl Bionics Biomech. 2020 Sep 17;2020:8882430. doi: 10.1155/2020/8882430. eCollection 2020.

Abstract

BACKGROUND

Spinal cord injury (SCI) is a common severe trauma in clinic, hundreds of thousands of people suffer from which every year in the world. In terms of injury location, cervical spinal cord injury (CSCI) has the greatest impact. After cervical spinal cord injury, the lack of innervated muscles is not enough to provide ventilation and other activities to complete the respiratory function. In addition to the decline of respiratory capacity, respiratory complications also have a serious impact on the life of patients. The most commonly used assisted breathing and cough equipment is the ventilator, but in recent years, the functional electrical stimulation method is being used gradually and widely.

METHODS

About hundred related academic papers are cited for data analysis. They all have the following characteristics: (1) basic conditions of patients were reported, (2) patients had received nerve or muscle stimulation and the basic parameters, and (3) the results were evaluated based on some indicators.

RESULTS

The papers mentioned above are classified as four kinds of stimulation methods: muscle electric/magnetic stimulation, spinal dural electric stimulation, intraspinal microstimulation, and infrared light stimulation. This paper describes the stimulation principle and application experiment. Finally, this paper will compare the indexes and effects of typical stimulation methods, as well as the two auxiliary methods: training and operation.

CONCLUSIONS

Although there is limited evidence for the treatment of respiratory failure by nerve or muscle stimulation after cervical spinal cord injury, the two techniques seem to be safe and effective. At the same time, light stimulation is gradually applied to clinical medicine with its strong advantages and becomes the development trend of nerve stimulation in the future.

摘要

背景

脊髓损伤(SCI)是临床上常见的严重创伤,全球每年有数十万人受其影响。就损伤部位而言,颈髓损伤(CSCI)影响最大。颈髓损伤后,失神经支配的肌肉不足以提供通气及其他活动来完成呼吸功能。除呼吸能力下降外,呼吸并发症也严重影响患者生命。最常用的辅助呼吸和咳嗽设备是呼吸机,但近年来,功能性电刺激方法正逐渐得到广泛应用。

方法

引用约一百篇相关学术论文进行数据分析。这些论文均具有以下特点:(1)报告了患者的基本情况;(2)患者接受了神经或肌肉刺激及基本参数;(3)基于某些指标对结果进行了评估。

结果

上述论文分为四种刺激方法:肌肉电/磁刺激、脊髓硬膜电刺激、脊髓内微刺激和红外光刺激。本文描述了刺激原理及应用实验。最后,本文将比较典型刺激方法的指标和效果,以及两种辅助方法:训练和手术。

结论

虽然颈髓损伤后通过神经或肌肉刺激治疗呼吸衰竭的证据有限,但这两种技术似乎安全有效。同时,光刺激凭借其强大优势逐渐应用于临床医学,成为未来神经刺激的发展趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97bc/7519444/bc71f81560cb/ABB2020-8882430.001.jpg

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