• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人体系统的功能生物动力学:一种具有生命周期中功能学习与衰老的数学公理体系。

Functional biodynamics of human-body system: A mathematical axiomatics with functional learning and aging in life cycle.

作者信息

Mau Jochen

机构信息

School of Medicine, Heinrich Heine University, 40225 Düsseldorf, Germany.

出版信息

Cogn Neurodyn. 2020 Oct;14(5):579-590. doi: 10.1007/s11571-020-09629-y. Epub 2020 Sep 5.

DOI:10.1007/s11571-020-09629-y
PMID:33014174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7501377/
Abstract

"Systems neuroergonomics" (Mau, J. In: R. Wang and X. Pan, editors, Advances in Cognitive Neurodynamics (V), chapter 59, pages 431-437, Springer Science+Business Media, Singapore, 2016) showed a separation of human-body system's functional organization from its cellular material in order to open a holistic perspective that can comprise all body functions. This was achieved with a strictly hierarchical structure in drill-down from system's functional whole to base functional elements. Implied multi-scale functional dynamics with coherent up-scaling were mathematically described in an axiomatic way, but the daily wake/sleep dynamics cover mainly anticipated functional challenges. Here, the theory is expanded to permit "functional learning" in the sense of adjustment of functional capacities to meet higher demand. "Functional aging" as a whole-body frailty is derived from biodynamic entropy that eventually drives the living to meet its inevitable destiny, death. The ages at which frailty begins to dominate can currently be obtained only from official life tables as population averages and are different for men and women, accordingly. The objective is to develop a mathematical theory in medicine from an axiomatic approach to phenomenological biodynamics, in which cognition is viewed as an embodied activity.

摘要

“系统神经工效学”(毛,J. 载于:王,R. 和潘,X. 编,《认知神经动力学进展(V)》,第59章,第431 - 437页,施普林格科学 + 商业媒体出版社,新加坡,2016年)展示了人体系统功能组织与其细胞物质的分离,以便开启一个能够涵盖所有身体功能的整体视角。这是通过从系统功能整体到基本功能要素的严格分层结构来实现的。隐含的具有连贯向上扩展的多尺度功能动力学以公理方式进行了数学描述,但日常的清醒/睡眠动力学主要涵盖预期的功能挑战。在此,该理论得到扩展,以允许在根据更高需求调整功能能力意义上的“功能学习”。作为全身虚弱的“功能衰老”源自生物动力学熵,最终驱使生命体走向其不可避免的命运——死亡。目前,虚弱开始占主导地位的年龄只能从官方生命表中获取作为人口平均值,并且男性和女性相应地有所不同。目标是从公理方法到现象学生物动力学发展医学中的数学理论,其中认知被视为一种具身活动。

相似文献

1
Functional biodynamics of human-body system: A mathematical axiomatics with functional learning and aging in life cycle.人体系统的功能生物动力学:一种具有生命周期中功能学习与衰老的数学公理体系。
Cogn Neurodyn. 2020 Oct;14(5):579-590. doi: 10.1007/s11571-020-09629-y. Epub 2020 Sep 5.
2
Recent advances in biodynamics of human hand-arm system.人类手臂系统生物动力学的最新进展。
Ind Health. 2005 Jul;43(3):449-71. doi: 10.2486/indhealth.43.449.
3
Hilbert's axiomatic method and Carnap's general axiomatics.希尔伯特的公理方法与卡尔纳普的一般公理系统
Stud Hist Philos Sci. 2015 Oct;53:12-22. doi: 10.1016/j.shpsa.2015.05.005. Epub 2015 Jun 9.
4
Toward the development of a vibrant, super-aged society: The future of medicine and society in Japan.迈向充满活力的超老龄社会:日本的医学与社会的未来。
Geriatr Gerontol Int. 2021 Aug;21(8):601-613. doi: 10.1111/ggi.14201. Epub 2021 Jul 1.
5
Japan as the front-runner of super-aged societies: Perspectives from medicine and medical care in Japan.日本作为超老龄化社会的领跑者:来自日本医学与医疗护理的视角
Geriatr Gerontol Int. 2015 Jun;15(6):673-87. doi: 10.1111/ggi.12450. Epub 2015 Feb 5.
6
Slow dynamics perspectives on the Embodied-Brain Systems Science.具身脑系统科学的慢动力学视角
Neurosci Res. 2016 Mar;104:52-5. doi: 10.1016/j.neures.2015.11.002. Epub 2015 Nov 28.
7
Irreversible thermodynamics in multiscale stochastic dynamical systems.多尺度随机动力系统中的不可逆热力学
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Apr;83(4 Pt 1):041130. doi: 10.1103/PhysRevE.83.041130. Epub 2011 Apr 27.
8
Order-Stability in Complex Biological, Social, and AI-Systems from Quantum Information Theory.基于量子信息论的复杂生物、社会和人工智能系统中的秩序稳定性
Entropy (Basel). 2021 Mar 16;23(3):355. doi: 10.3390/e23030355.
9
[Complexity of the phenomenon of life - the challenge for medicine].[生命现象的复杂性——医学面临的挑战]
Wiad Lek. 2017;70(2 pt 2):251-260.
10
[Acquired drives. The cortical mechanism responsible to the emergence and development of social existence].[习得性驱力。负责社会存在出现与发展的皮质机制]
Neuropsychopharmacol Hung. 2007 Oct;9(3):151-66.

引用本文的文献

1
Principles of Endocrine Regulation: Reconciling Tensions Between Robustness in Performance and Adaptation to Change.内分泌调节原理:在性能稳健性和对变化的适应之间协调矛盾。
Front Endocrinol (Lausanne). 2022 Jun 9;13:825107. doi: 10.3389/fendo.2022.825107. eCollection 2022.

本文引用的文献

1
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.溶血性神经酰胺失衡引起的基因组完整性丧失导致心脏衰老。
EMBO Rep. 2019 Apr;20(4). doi: 10.15252/embr.201847407. Epub 2019 Mar 18.
2
The number of key carcinogenic events can be predicted from cancer incidence.致癌事件的关键数量可以从癌症发病率中预测出来。
Sci Rep. 2017 Sep 22;7(1):12170. doi: 10.1038/s41598-017-12448-7.
3
Systematic review of high-intensity progressive resistance strength training of the lower limb compared with other intensities of strength training in older adults.系统回顾高强度渐进式抗阻下肢力量训练与老年人其他强度力量训练的比较。
Arch Phys Med Rehabil. 2013 Aug;94(8):1458-72. doi: 10.1016/j.apmr.2013.02.022. Epub 2013 Mar 7.
4
Brain energy consumption induced by electrical stimulation promotes systemic glucose uptake.电刺激引起的大脑能量消耗促进全身葡萄糖摄取。
Biol Psychiatry. 2011 Oct 1;70(7):690-5. doi: 10.1016/j.biopsych.2011.05.009. Epub 2011 Jun 24.
5
Transcranial direct current stimulation facilitates decision making in a probabilistic guessing task.经颅直流电刺激促进概率猜测任务中的决策。
J Neurosci. 2010 Mar 24;30(12):4241-5. doi: 10.1523/JNEUROSCI.2924-09.2010.
6
Enhancement of planning ability by transcranial direct current stimulation.经颅直流电刺激增强计划能力。
J Neurosci. 2009 Jun 3;29(22):7271-7. doi: 10.1523/JNEUROSCI.0065-09.2009.
7
The selfish brain: competition for energy resources.自私的大脑:对能量资源的争夺
Neurosci Biobehav Rev. 2004 Apr;28(2):143-80. doi: 10.1016/j.neubiorev.2004.03.002.
8
A generalized multihit dose-response model for low-dose extrapolation.
Biometrics. 1981 Jun;37(2):341-52.