采用响应面法利用大米淀粉去除水中的头孢克肟
Removal of Cefixime from Water Using Rice Starch by Response Surface Methodology.
作者信息
Tabatabaei Fatemeh Sadat, Asadi-Ghalhari Mahdi, Aali Rahim, Mohammadi Fatemeh, Mostafaloo Roqiyeh, Esmaeili Rezvaneh, Davarparast Zohreh, Safari Zahra
机构信息
Department of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran.
出版信息
Avicenna J Med Biotechnol. 2020 Oct-Dec;12(4):230-235.
BACKGROUND
Remaining pharmaceutical compounds cause environmental pollution. Therefore, refining these compounds has become a major challenge. In this study, the function of eliminating Cefixime (CFX) using rice starch was evaluated under controlled conditions.
METHODS
Response Surface Methodology (RSM) was used to design, analyze, and optimize experiments, and the interaction between four variables including pH (3-9), rice starch dose (0-300 ), CFX initial concentration (0-16 ) and time (20-120 ) was investigated on CFX removal.
RESULTS
The optimum pH, starch dose, initial concentration and time were 4.5, 225 , 7.9 and 95 , respectively. The maximum efficiency of CFX removal was 70.22%. According to RSM, this study follows a quadratic model (R=0.954).
CONCLUSION
Rice starch has been successful in removing CFX from the aqueous solution. Therefore, it is recommended to utilize this process to remove CFX from aqueous solutions.
背景
残留的药物化合物会造成环境污染。因此，提纯这些化合物已成为一项重大挑战。在本研究中，在可控条件下评估了利用大米淀粉去除头孢克肟（CFX）的功能。
方法
采用响应面法（RSM）设计、分析和优化实验，并研究了pH值（3 - 9）、大米淀粉剂量（0 - 300）、CFX初始浓度（0 - 16）和时间（20 - 120）这四个变量之间的相互作用对CFX去除效果的影响。
结果
最佳pH值、淀粉剂量、初始浓度和时间分别为4.5、225、7.9和95。CFX的最大去除效率为70.22%。根据响应面法，本研究遵循二次模型（R = 0.954）。
结论
大米淀粉已成功从水溶液中去除CFX。因此，建议采用此方法从水溶液中去除CFX。
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