生物标志物在心肌纤维化中的作用。
Roles of Biomarkers in Myocardial Fibrosis.
作者信息
Ding Yuejia, Wang Yuan, Zhang Wanqin, Jia Qiujin, Wang Xiaoling, Li Yanyang, Lv Shichao, Zhang Junping
机构信息
1First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
3Qian'an Hospital of Traditional Chinese Medicine, Qian'an 064400, China.
出版信息
Aging Dis. 2020 Oct 1;11(5):1157-1174. doi: 10.14336/AD.2020.0604. eCollection 2020 Oct.
Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the diagnosis of myocardial fibrosis, has limitations in terms of clinical application. Therefore, biomarkers have been recommended for noninvasive assessment of myocardial fibrosis. This review discusses the role of biomarkers in myocardial fibrosis from the perspective of collagen.
心肌纤维化在多种心血管疾病中均有观察到，并且在心脏功能损害中起关键作用。心内膜心肌活检作为诊断心肌纤维化的金标准，在临床应用方面存在局限性。因此，推荐使用生物标志物对心肌纤维化进行无创评估。本综述从胶原蛋白的角度探讨了生物标志物在心肌纤维化中的作用。
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