用于近距离后装治疗过程中实时体内剂量监测的光纤剂量计。
Optical fiber dosimeter for real-time in-vivo dose monitoring during LDR brachytherapy.
作者信息
Woulfe P, Sullivan F J, Kam W, O'Keeffe S
机构信息
Optical Fiber Sensors Research Centre, University of Limerick, Ireland.
Dept. of Radiotherapy Physics, Galway Clinic, Ireland.
出版信息
Biomed Opt Express. 2020 Jun 30;11(7):4027-4036. doi: 10.1364/BOE.385610. eCollection 2020 Jul 1.
Abstract
An optical fiber sensor for monitoring low dose radiation is presented. The sensor, based on radiation sensitive scintillation material, terbium doped gadolinium oxysulphide (GdOS:Tb), is embedded in a cavity of 700µm diameter within a 1mm plastic optical fiber. The sensor is compared with the treatment planning system for repeatability, angular dependency, distance and accumulated radiation activity. The sensor demonstrates a high sensitivity of 152 photon counts/Gy with a temporal resolution of 0.1 seconds, with the largest repeatability error of 4.1%, to 0.361mCi of Iodine-125 the radioactive source most commonly used in LDR brachytherapy for treating prostate cancer.
摘要
介绍了一种用于监测低剂量辐射的光纤传感器。该传感器基于辐射敏感闪烁材料——掺铽硫氧化钆（GdOS:Tb），嵌入在一根1mm塑料光纤内直径为700µm的腔体内。将该传感器与治疗计划系统在重复性、角度依赖性、距离和累积辐射活性方面进行了比较。该传感器对用于前列腺癌近距离治疗的最常用放射性源——125碘，在0.361mCi时表现出152光子计数/戈瑞的高灵敏度，时间分辨率为0.1秒，最大重复性误差为4.1%。
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