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一只短腿猎狗幼犬患卡氏肺孢子虫病。

Pneumocystosis in a lurcher puppy.

作者信息

Giannoulopoulos George, Lobetti Remo

机构信息

Wilson Veterinary Group, 5-11 Tenters Street, Bishop Auckland, County Durham, United Kingdom.

Bryanston Veterinary Hospital, 6 Ballyclare Drive, Bryanston, Johannesburg, South Africa.

出版信息

Med Mycol Case Rep. 2020 Sep 22;30:15-18. doi: 10.1016/j.mmcr.2020.09.003. eCollection 2020 Dec.

DOI:10.1016/j.mmcr.2020.09.003
PMID:33014701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7522037/
Abstract

A 10-month-old lurcher with history of recurrent skin problems, presented with tachypnoea which had progressively become severe. Investigations included haematology, serum biochemistry, blood coagulation profile, diagnostic imaging, bronchoscopy and bronchoalveolar lavage (BAL). Cytological evaluation of the BAL revealed the presence of Pneumocystis cysts. The patient was euthanased on humane grounds prior to treatment against Pneumocystosis. To the best of our knowledge this is the first case of Pneumocystosis in a lurcher puppy.

摘要

一只10个月大的格力犬,有反复出现皮肤问题的病史,出现了逐渐加重的呼吸急促症状。检查包括血液学、血清生化、凝血指标、诊断性影像学、支气管镜检查和支气管肺泡灌洗(BAL)。BAL的细胞学评估显示存在肺孢子虫囊肿。在针对肺孢子虫病进行治疗之前,出于人道考虑对该患者实施了安乐死。据我们所知,这是首例格力幼犬患肺孢子虫病的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4f/7522037/e494296e658f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4f/7522037/b36a5768591b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4f/7522037/e494296e658f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4f/7522037/b36a5768591b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4f/7522037/e494296e658f/gr2.jpg

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本文引用的文献

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Disseminated Pneumocystosis in a Toy Poodle.一只玩具贵宾犬的播散性肺孢子菌病
J Comp Pathol. 2020 Feb;175:85-89. doi: 10.1016/j.jcpa.2019.12.009. Epub 2020 Feb 7.
2
Pneumocystis carinii infection with severe pneumomediastinum and lymph node involvement in a Whippet mixed-breed dog.一只惠比特混血犬发生卡氏肺孢子虫感染,伴有严重的纵隔气肿和淋巴结受累。
J Vet Diagn Invest. 2017 Sep;29(5):757-762. doi: 10.1177/1040638717710237. Epub 2017 May 26.
3
Molecular diagnosis of Pneumocystis pneumonia in dogs.犬肺孢子菌肺炎的分子诊断
Med Mycol. 2017 Nov 1;55(8):828-842. doi: 10.1093/mmy/myx007.
4
Evaluation of PCR in bronchoalveolar lavage fluid for diagnosis of Pneumocystis jirovecii pneumonia: a bivariate meta-analysis and systematic review.支气管肺泡灌洗液中 PCR 检测用于诊断卡氏肺孢子虫肺炎的评价:二项混合荟萃分析和系统综述。
PLoS One. 2013 Sep 4;8(9):e73099. doi: 10.1371/journal.pone.0073099. eCollection 2013.
5
The ecology of pneumocystis: perspectives, personal recollections, and future research opportunities.卡氏肺孢子虫生态学:观点、个人回忆和未来的研究机会。
J Eukaryot Microbiol. 2013 Nov-Dec;60(6):634-45. doi: 10.1111/jeu.12072. Epub 2013 Sep 3.
6
Reconstructing the early evolution of Fungi using a six-gene phylogeny.利用六基因系统发育重建真菌的早期进化
Nature. 2006 Oct 19;443(7113):818-22. doi: 10.1038/nature05110.
7
Immunoglobulin deficiency in Cavalier King Charles Spaniels with Pneumocystis pneumonia.患有卡氏肺孢子虫肺炎的骑士查理王小猎犬的免疫球蛋白缺乏症。
J Vet Intern Med. 2006 May-Jun;20(3):523-7. doi: 10.1892/0891-6640(2006)20[523:idickc]2.0.co;2.
8
Pneumocystis pneumonia.肺孢子菌肺炎
N Engl J Med. 2004 Jun 10;350(24):2487-98. doi: 10.1056/NEJMra032588.
9
Characterization of transmission of Pneumocystis carinii f. sp. muris through immunocompetent BALB/c mice.卡氏肺孢子虫鼠亚种通过免疫健全的BALB/c小鼠传播的特征描述。
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Common variable immunodeficiency in miniature dachshunds affected with Pneumonocystis carinii pneumonia.患卡氏肺孢子虫肺炎的迷你腊肠犬的常见可变免疫缺陷。
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