酿酒酵母RNA1基因破坏导致的多体性促进的染色体特异性
Chromosome specificity of polysomy promotion by disruptions of the Saccharomyces cerevisiae RNA1 gene.
作者信息
Atkinson N S, Hopper A K
出版信息
Genetics. 1987 Jul;116(3):371-5. doi: 10.1093/genetics/116.3.371.
Abstract
Previously, we showed that a disruption of the yeast RNA1 gene with LEU2 sequences promotes polysomy for chromosome XIII. Here we demonstrate that this phenotype is due to sequences specific to the RNA1 gene and that the disruption allele does not affect nondisjunction of three other chromosomes or polysomy of a minichromosome. Hence polysomy appears to be restricted to chromosome XIII.
摘要
此前，我们发现用LEU2序列破坏酵母RNA1基因会促进第十三条染色体的多体性。在此我们证明，这种表型是由RNA1基因特有的序列导致的，并且该破坏等位基因不影响其他三条染色体的不分离或小染色体的多体性。因此，多体性似乎仅限于第十三条染色体。
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本文引用的文献
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