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用于基于心电图的稳健端到端心跳分类的对抗多任务学习

Adversarial Multi-Task Learning for Robust End-to-End ECG-based Heartbeat Classification.

作者信息

Shahin Mostafa, Oo Ethan, Ahmed Beena

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:341-344. doi: 10.1109/EMBC44109.2020.9175640.

Abstract

In clinical practice, heart arrhythmias are manually diagnosed by a doctor, which is a time-consuming process. Furthermore, this process is error-prone due to noise from the recording equipment and biological non-idealities of patients. Thus, an automated arrhythmia classifier would be time and cost-effective as well as offer better generalization across patients. In this paper, we propose an adversarial multitask learning method to improve the generalization of heartbeat arrythmia classification. We built an end-to-end deep neural network (DNN) system consisting of three sub-networks; a generator, a heartbeat-type discriminator, and a subject (or patient) discriminator. Each of these two discriminators had its own loss function to control its impact. The generator was "friendly" to the heartbeat-type discrimination task by minimizing its loss function and "hostile" to the subject discrimination task by maximizing its loss function. The network was trained using raw ECG signals to discriminate between five types of heartbeats - normal heartbeats, right bundle branch blocks (RBBB), premature ventricular contractions (PVC), paced beats (PB) and fusion of ventricular and normal beats (FVN). The method was tested with the MIT-BIH arrhythmia dataset and achieved a 17% reduction in classification error compared to a baseline using a fully-connected DNN classifier.Clinical Relevance-This work validates that it is possible to develop a subject-independent automated heart arrhythmia detection system to assist clinicians in the diagnosis process.

摘要

在临床实践中,心律失常由医生手动诊断,这是一个耗时的过程。此外,由于记录设备产生的噪声以及患者的生物非理想情况,这个过程容易出错。因此,一个自动心律失常分类器既节省时间又具有成本效益,并且能在不同患者中实现更好的泛化。在本文中,我们提出一种对抗多任务学习方法来提高心跳心律失常分类的泛化能力。我们构建了一个由三个子网络组成的端到端深度神经网络(DNN)系统;一个生成器、一个心跳类型判别器和一个主体(或患者)判别器。这两个判别器各自有其损失函数来控制其影响。生成器通过最小化其损失函数对心跳类型判别任务“友好”,并通过最大化其损失函数对主体判别任务“敌对”。该网络使用原始心电图信号进行训练,以区分五种心跳类型——正常心跳、右束支传导阻滞(RBBB)、室性早搏(PVC)、起搏心跳(PB)以及室性与正常心跳融合(FVN)。该方法在麻省理工学院 - 贝斯以色列女执事医疗中心心律失常数据集上进行了测试,与使用全连接DNN分类器的基线相比,分类误差降低了17%。临床相关性——这项工作验证了开发一个独立于主体的自动心律失常检测系统以协助临床医生进行诊断过程是可行的。

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