Lu Jiaping, Zhang Naizheng, Qian Wenhao
Department of Stomatology, Shanghai Xuhui District Dental Center, Shanghai, China.
Medicine (Baltimore). 2020 Oct 2;99(40):e22588. doi: 10.1097/MD.0000000000022588.
The objective of this meta-analysis was to summarize and identify the available evidence from studies to estimate the clinical value of traditional Chinese medicine (TCM) in the treatment of recurrent aphthous stomatitis (RAS) and provides clinicians with evidence on which to base their clinical decision making.
This review will include all studies comparing clinical efficacy of TCM in the treatment of RAS. The search strategy will be performed in 9 databases. We will not establish any limitations to language and publication status, published from inception to the August 2020. Two reviewers will screen, select studies, extract data, and assess quality independently. Outcome is clinical efficacy, pain relief, duration of wound healing, effect on wound healing, rate of recurrence, adverse events, and safety. The methodological quality including the risk of bias of the included studies will be evaluated. We will carry out statistical analysis using RevMan 5.3 software.
This study will summarize current evidence to assess the efficacy and safety of TCM in the treatment of RAS.
The findings of this study will provide helpful evidence for the clinician, and will promote further studies, as well as studying the value of TCM.
INPLASY202080126 (DOI number: 10.37766/inplasy2020.8.0126).
本荟萃分析的目的是总结并识别研究中的现有证据，以评估中医治疗复发性阿弗他口炎（RAS）的临床价值，并为临床医生提供临床决策依据。
本综述将纳入所有比较中医治疗RAS临床疗效的研究。检索策略将在9个数据库中进行。我们将不对语言和发表状态设置任何限制，检索时间从开始到2020年8月。两名评审员将独立进行筛选、选择研究、提取数据和评估质量。结局指标为临床疗效、疼痛缓解、伤口愈合持续时间、对伤口愈合的影响、复发率、不良事件和安全性。将评估包括纳入研究的偏倚风险在内的方法学质量。我们将使用RevMan 5.3软件进行统计分析。
本研究将总结当前证据，以评估中医治疗RAS的疗效和安全性。
本研究结果将为临床医生提供有用的证据，并将促进进一步的研究以及对中医价值的研究。
INPLASY202080126（DOI编号：10.37766/inplasy2020.8.0126）。
