Stinnett E, Rodu B, Grizzle W E
J Am Dent Assoc. 1987 Jun;114(6):814-6. doi: 10.14219/jada.archive.1987.0162.
In approximately half of the patients taking phenytoin, gingival fibroblasts proliferate, causing tissue overgrowth and gingival hyperplasia. Recent clinical and basic research is reviewed, describing the conditions associated with phenytoin therapy and gingival hyperplasia.
在服用苯妥英钠的患者中,约有一半会出现牙龈成纤维细胞增殖,导致组织过度生长和牙龈增生。本文综述了近期的临床和基础研究,描述了与苯妥英钠治疗及牙龈增生相关的情况。