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土壤杀线虫剂1,3 - 二氯丙烯的体外致突变性

In vitro mutagenicity of the soil nematicide 1,3-dichloropropene.

作者信息

Neudecker T, Stefani A, Henschler D

出版信息

Experientia. 1977 Aug 15;33(8):1084-5. doi: 10.1007/BF01945985.

DOI:10.1007/BF01945985
PMID:330205
Abstract

The cis- and trans-isomers of 1,3-dichloropropene have been tested in the Ames mutagenicity assay system on Salmonella typhimurium tester strain TA 1535. Both isomers have been found to be mutagenic even without microsomal activation.

摘要

1,3 - 二氯丙烯的顺式和反式异构体已在鼠伤寒沙门氏菌测试菌株TA 1535的艾姆斯诱变试验系统中进行了测试。结果发现，即使没有微粒体激活，两种异构体都具有致突变性。

相似文献

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In vitro mutagenicity of the soil nematicide 1,3-dichloropropene.土壤杀线虫剂1,3 - 二氯丙烯的体外致突变性
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引用本文的文献

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A study of well water in selected California communities for residues of 1,3-dichloropropene, chloroallyl alcohol and 49 organophosphate or chlorinated hydrocarbon pesticides.
Bull Environ Contam Toxicol. 1982 Sep;29(3):354-9. doi: 10.1007/BF01706240.
2
Identification and quantitative determination of mercapturic acids formed from Z- and E-1,3-dichloropropene by the rat, using gas chromatography with three different detection techniques.采用三种不同检测技术的气相色谱法，对大鼠体内由Z-和E-1,3-二氯丙烯形成的硫醚氨酸进行鉴定和定量测定。
Arch Toxicol. 1986 Dec;59(4):235-41. doi: 10.1007/BF00290544.
3
Overview of potential mutagenic problems posed by some pesticides and their trace impurities.某些农药及其微量杂质所引发的潜在诱变问题概述。

本文引用的文献

1
Acetylornithinase of Escherichia coli: partial purification and some properties.大肠杆菌的乙酰鸟氨酸酶：部分纯化及某些性质
J Biol Chem. 1956 Jan;218(1):97-106.
2
Oncogenic response of rat skin, lungs, and bones to vinyl chloride.大鼠皮肤、肺和骨骼对氯乙烯的致癌反应。
Cancer Res. 1971 May;31(5):516-22.
3
Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.致癌物是诱变剂：一种将用于活化的肝脏匀浆和用于检测的细菌相结合的简单测试系统。
Environ Health Perspect. 1978 Dec;27:125-31. doi: 10.1289/ehp.7827125.
Proc Natl Acad Sci U S A. 1973 Aug;70(8):2281-5. doi: 10.1073/pnas.70.8.2281.
4
Liver-microsome-mediated formation of alkylating agents from vinyl bromide and vinyl chloride.肝脏微粒体介导的由溴乙烯和氯乙烯形成烷基化剂的过程。
Biochem Biophys Res Commun. 1975 Nov 17;67(2):596-603. doi: 10.1016/0006-291x(75)90854-2.
5
Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxiran formation.作为代谢环氧乙烷形成的函数，氯乙烯的体外诱变性和潜在致癌性。
Biochem Pharmacol. 1975 Nov 1;24(21):2013-7. doi: 10.1016/0006-2952(75)90396-2.
6
Human, rat and mouse liver-mediated mutagenicity of vinyl chloride in S. typhimurium strains.人、大鼠和小鼠肝脏介导的氯乙烯在鼠伤寒沙门氏菌菌株中的致突变性。
Int J Cancer. 1975 Mar 15;15(3):429-37. doi: 10.1002/ijc.2910150309.
7
Tissue-mediated mutagenicity of vinylidene chloride and 2-chlorobutadiene in Salmonella typhimurium.
Nature. 1975 Jun 19;255(5510):641-3. doi: 10.1038/255641a0.
8
Interim results of exposure of rats, hamsters, and mice to vinyl chloride.大鼠、仓鼠和小鼠接触氯乙烯的中期结果。
Ann N Y Acad Sci. 1975 Jan 31;246:219-24. doi: 10.1111/j.1749-6632.1975.tb51095.x.
9
Liver microsomal uptake of (14C)vinyl chloride and transformation to protein alkylating metabolites in vitro.体外肝脏微粒体对（14C）氯乙烯的摄取及向蛋白质烷基化代谢物的转化
Toxicol Appl Pharmacol. 1976 Sep;37(3):461-71. doi: 10.1016/0041-008x(76)90208-8.