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咖啡饮用与胃癌的反比关系:一项生态学研究。

Coffee Consumption and Its Inverse Relationship with Gastric Cancer: An Ecological Study.

机构信息

Facultad de Ciencias de la Salud, Universidad Icesi, Cali 760032, Valle del Cauca, Colombia.

Centro de Investigaciones Clínicas (CIC), Fundación Valle del Lili, Cali 760032, Valle del Cauca, Colombia.

出版信息

Nutrients. 2020 Oct 2;12(10):3028. doi: 10.3390/nu12103028.

DOI:10.3390/nu12103028
PMID:33023243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7601092/
Abstract

Coffee is the second most popular drink worldwide, and it has various components with antioxidant and antitumor properties. Due to its chemical composition, it could act as an antitumor substance in the gastrointestinal tract. The objective of this study was to explore the relationship between coffee consumption and the incidence/mortality of stomach cancer in the highest-consuming countries. An ecological study using Spearman's correlation coefficient was performed. The WorldAtlas's dataset of coffee consumption and the incidence/mortality rates database of the International Agency for Research were used as sources of information. A total of 25 countries were entered to the study. There was an inverse linear correlation between coffee consumption in kg per person per year and estimated age-adjusted incidence ( = 0.5984, = 0.0016) and mortality ( = 0.5877, = 0.0020) of stomach cancer. Coffee may potentially have beneficial effects on the incidence and mortality of stomach cancer, as supported by the data from each country analyzed.

摘要

咖啡是全球第二大受欢迎的饮品,它含有多种具有抗氧化和抗肿瘤特性的成分。由于其化学组成,咖啡可能在胃肠道中起到抗肿瘤物质的作用。本研究的目的是探讨咖啡消费与最高消费国家胃癌发病率/死亡率之间的关系。采用斯皮尔曼相关系数进行了一项生态学研究。使用 WorldAtlas 的咖啡消费数据集和国际癌症研究机构的发病率/死亡率数据库作为信息来源。共有 25 个国家纳入研究。咖啡人均年消费量(以公斤计)与估计的年龄调整发病率( = 0.5984, = 0.0016)和死亡率( = 0.5877, = 0.0020)呈负线性相关。分析每个国家的数据均表明,咖啡可能对胃癌的发病率和死亡率有有益影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/042b/7601092/38dce5442d3d/nutrients-12-03028-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/042b/7601092/b72de1e7c07d/nutrients-12-03028-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/042b/7601092/38dce5442d3d/nutrients-12-03028-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/042b/7601092/b72de1e7c07d/nutrients-12-03028-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/042b/7601092/38dce5442d3d/nutrients-12-03028-g002.jpg

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咖啡饮用/体育锻炼与胃癌、肝癌、结肠癌、乳腺癌、宫颈癌、肺癌、甲状腺癌、前列腺癌和膀胱癌的相关性研究。
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按类型划分的咖啡摄入量与消化道癌症风险:一项大型前瞻性队列研究。
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