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寻常痤疮患者中的酒渣鼻:亚型分布和诱因评估——一项横断面研究。

Rosacea in acne vulgaris patients: Subtype distribution and triggers assessment-A cross-sectional study.

机构信息

Department of Dermatology and Venereology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

出版信息

J Cosmet Dermatol. 2021 Jun;20(6):1889-1896. doi: 10.1111/jocd.13762. Epub 2020 Oct 26.

Abstract

BACKGROUND

Recent studies have reported that the incidence of acne combined with rosacea is increasing. However, the clinical feature and inducing factor of these two diseases co-occurrence is remain unclear.

AIMS

This study aims to investigate the classification and severity of female patients combining with acne and rosacea.

PATIENTS/METHODS: Female patients with facial acne combined with rosacea, 15-50 years old, were included from dermatology outpatient department from January 2019 to December 2019. The severity of acne was classified according to the Pillsbury grading system. Rosacea was diagnosed and classified according to the Standard issued by National Rosacea Society Expert Committee. Questionnaire was designed to collect the information of rosacea triggers from each patient.

RESULTS

563 vulgaris acne combined with rosacea patients (mean age 23.2 ± 43), included 70.33% severe acne (n = 396), 15.81% moderate acne(n = 89), and 13.85% mild acne(n = 78), had finished the study. In severe acne group, 72.47% combine with erythematotelangiectatic rosacea (ETR), 22.47% combined with papulopustular rosacea (PPR), and 5.05% combine with phymatous rosacea (PHR). In moderate acne group, 53.93% combine with ETR, 43.82% combined with papulopustular rosacea (PPR), and 2.24% combine with PHR. All patients in moderate acne subject group was combined with ETR (100%). Patients that did not use skin care produces presented 12.79 times higher rate to combine with ETR than that frequently using skin care products (P = .014).

CONCLUSIONS

Erythema telangiectasia rosacea is the most common rosacea type in female acne patients. There is a need to be vigilant about the combination of sever/moderate acne and papulopustular rosacea. Rational daily use of skin care products can reduce the incidence of rosacea in acne patients. For acne patients without family history of rosacea, dermatologists should also not ignore the healthy education to avoid potential triggers of rosacea.

摘要

背景

最近的研究报告称,痤疮合并酒渣鼻的发病率正在上升。然而,这两种疾病同时发生的临床特征和诱发因素仍不清楚。

目的

本研究旨在探讨女性痤疮合并酒渣鼻患者的分类和严重程度。

患者/方法:纳入 2019 年 1 月至 2019 年 12 月皮肤科门诊 15-50 岁女性面部痤疮合并酒渣鼻患者。根据 Pillsbury 分级系统对痤疮严重程度进行分类。根据国家酒渣鼻学会专家委员会发布的标准诊断和分类酒渣鼻。设计问卷收集每位患者酒渣鼻诱因的信息。

结果

563 例寻常型痤疮合并酒渣鼻患者(平均年龄 23.2 ± 43),其中重度痤疮 70.33%(n=396)、中度痤疮 15.81%(n=89)、轻度痤疮 13.85%(n=78)完成了研究。在重度痤疮组中,72.47%合并红斑毛细血管扩张性酒渣鼻(ETR),22.47%合并丘疹脓疱性酒渣鼻(PPR),5.05%合并肥大性酒渣鼻(PHR)。在中度痤疮组中,53.93%合并 ETR,43.82%合并丘疹脓疱性酒渣鼻(PPR),2.24%合并 PHR。中度痤疮组所有患者均合并 ETR(100%)。与经常使用护肤品的患者相比,不使用护肤品的患者合并 ETR 的几率高 12.79 倍(P=.014)。

结论

红斑毛细血管扩张性酒渣鼻是女性痤疮患者中最常见的酒渣鼻类型。需要警惕重度/中度痤疮与丘疹脓疱性酒渣鼻的合并。合理的日常使用护肤品可以降低痤疮患者酒渣鼻的发生率。对于无酒渣鼻家族史的痤疮患者,皮肤科医生也不应忽视酒渣鼻潜在诱因的健康教育。

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