Noguchi Ryoko, Hamada Chuya, Shimoji Koki
Department of Anesthesiology, Niigata University School of Medicine, Niigata 951 Japan Department of Virology, Niigata University School of Medicine, Niigata 951 Japan.
Pain. 1987 Jun;29(3):387-392. doi: 10.1016/0304-3959(87)90053-4.
Adult male rats, which had electrodes chronically implanted in the periaqueductal gray (PAG), were immunized with sheep red blood cells (SRBCs). The number of direct and indirect plaque-forming cells (PFCs) in the group receiving PAG stimulation after immunization did not differ significantly from that in the unstimulated group. Thus, the results indicate that short-term PAG stimulation does not suppress antibody-producing activity in the rat.
成年雄性大鼠的中脑导水管周围灰质(PAG)长期植入电极,然后用绵羊红细胞(SRBC)进行免疫。免疫后接受PAG刺激组的直接和间接空斑形成细胞(PFC)数量与未刺激组相比无显著差异。因此,结果表明短期PAG刺激不会抑制大鼠的抗体产生活性。