Gardère J J, de Barbeyrac B, Penouil F, Louis C, Brachet-Liermain A, Favarel-Garrigues J C
Pathol Biol (Paris). 1987 May;35(5):608-12.
Ceftriaxone was used in 24 medical intensive care patients to treat 8 pulmonary infections, 12 septicaemias, 3 urinary tract infections, 1 meningitis. It was administered at a single intravenous dose of 2 g every 24 h. The therapy was successful, clinically and bacteriologically in 16 patients. The reasons of the failures are analysed. Plasma concentrations were obtained: they demonstrate that ceftriaxone is effective when given once a day in most cases.
头孢曲松用于24例医学重症监护患者,治疗8例肺部感染、12例败血症、3例尿路感染、1例脑膜炎。给药方式为每24小时静脉注射单剂量2克。16例患者在临床和细菌学方面治疗成功。分析了治疗失败的原因。测定了血浆浓度:结果表明,大多数情况下每日给药一次时头孢曲松是有效的。