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心脏起搏器诊所:昔日的记忆。

The Cardiac Pacemaker Clinic: Memories From a Bygone Era.

机构信息

Department of Cardiology, The Royal Melbourne Hospital and the Department of Medicine, University of Melbourne, Melbourne, Vic, Australia.

Cardiovascular Unit, Epworth Hospital, Melbourne, Vic, Australia.

出版信息

Heart Lung Circ. 2021 Feb;30(2):216-224. doi: 10.1016/j.hlc.2020.08.020. Epub 2020 Oct 5.

Abstract

In 1963, soon after the first ventricular pacemakers were implanted at the Royal Melbourne Hospital, attempts were made to identify impending pacing failure, thus preventing sudden death in these very vulnerable patients. By 1970, patient numbers had increased, a formal regular pacemaker clinic was established, and guidelines and protocols developed. The clinic was staffed by a physician, a biomedical engineer and cardiac technicians. The unipolar, asynchronous, non-programmable pulse generators were powered by mercuric oxide/zinc batteries and implanted in the abdomen, using either transvenous or epimyocardial leads. Although, pulse generators were electively replaced at 3 years, most had already been replaced because of power source depletion, electronic failure or lead issues. Testing in all patients involved an electrocardiographic rhythm strip and electronic analysis of the stimulus artefact using a calibrated high-speed storage oscilloscope. Results were compared to previous studies and significant changes were interpreted as impending power source depletion. As a result of this testing, 97% of cases of impending power source depletion were detected prior to failure. These findings allowed testing each 4 months and for pulse generator life to be extended beyond three years. With ventricular triggered pulse generators, new testing procedures were designed. With time, visiting regional centres and clinical evaluation of new products became important functions of the clinic.

摘要

1963 年,在皇家墨尔本医院首次植入心室起搏器后不久,人们就开始尝试识别即将发生的起搏失败,从而防止这些非常脆弱的患者猝死。到 1970 年,患者数量增加,正式的定期起搏器诊所成立,并制定了指南和协议。该诊所由一名医生、一名生物医学工程师和心脏技术人员组成。单极、异步、非程控脉冲发生器由氧化汞/锌电池供电,并通过经静脉或心外膜导联植入腹部。尽管脉冲发生器可以在 3 年后选择性更换,但由于电源耗尽、电子故障或导联问题,大多数已经更换。所有患者的测试都涉及心电图节律带和使用校准高速存储示波器对刺激伪影进行电子分析。将结果与以前的研究进行比较,将显著变化解释为即将发生的电源耗尽。由于这项测试,在电源耗尽之前,97%的潜在电源耗尽病例被发现。这些发现使得可以每 4 个月进行一次测试,并将脉冲发生器的寿命延长至三年以上。随着心室触发脉冲发生器的出现,设计了新的测试程序。随着时间的推移,访问区域中心和对新产品的临床评估成为诊所的重要功能。

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