Department of Neurology, Danderyd hospital, Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Nat Commun. 2020 Oct 8;11(1):5064. doi: 10.1038/s41467-020-18848-0.
SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies against SARS-CoV-2 was 19.1% among the 2149 healthcare workers recruited between April 14th and May 8th 2020, which was higher than the reported regional seroprevalence during the same time period. Symptoms associated with seroprevalence were anosmia (odds ratio (OR) 28.4, 95% CI 20.6-39.5) and ageusia (OR 19.2, 95% CI 14.3-26.1). Seroprevalence was also associated with patient contact (OR 2.9, 95% CI 1.9-4.5) and covid-19 patient contact (OR 3.3, 95% CI 2.2-5.3). These findings imply an occupational risk for SARS-CoV-2 infection among healthcare workers. Continued measures are warranted to assure healthcare workers safety and reduce transmission from healthcare workers to patients and to the community.
SARS-CoV-2 可能对医护人员构成职业健康风险。在这里，我们报告了瑞典一家大型急症医院的医护人员中 SARS-CoV-2 抗体的血清流行率、自我报告的症状和 SARS-CoV-2 的职业暴露情况。在 2020 年 4 月 14 日至 5 月 8 日期间招募的 2149 名医护人员中，针对 SARS-CoV-2 的 IgG 抗体血清阳性率为 19.1%，高于同期报告的区域性血清阳性率。与血清阳性相关的症状有嗅觉丧失（比值比 (OR) 28.4，95%置信区间 20.6-39.5）和味觉丧失（OR 19.2，95%置信区间 14.3-26.1）。血清阳性率也与患者接触（OR 2.9，95%置信区间 1.9-4.5）和新冠病毒患者接触（OR 3.3，95%置信区间 2.2-5.3）有关。这些发现意味着医护人员感染 SARS-CoV-2 的职业风险。需要继续采取措施确保医护人员的安全，并减少医护人员向患者和社区传播的风险。
