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恙虫病导致一名孕妇急性肝衰竭

Scrub Typhus Leading to Acute Liver Failure in a Pregnant Patient.

作者信息

Gaba Saurabh, Sharma Sanjana, Gaba Nayana, Gupta Monica

机构信息

General Medicine, Government Medical College and Hospital, Chandigarh, IND.

Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.

出版信息

Cureus. 2020 Sep 1;12(9):e10191. doi: 10.7759/cureus.10191.

DOI:10.7759/cureus.10191
PMID:33033671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7532875/
Abstract

Scrub typhus is a mite-borne rickettsial infection that presents with fever and a diverse array of complications. Lately, many epidemics have been reported from the Indian subcontinent. Data from these outbreaks suggest that liver injury in scrub typhus is common and reversible. We are reporting the case of a 27-year-old pregnant female who presented with fever, encephalopathy, jaundice and seizure. She had acute liver failure and dead fetus on admission. Despite appropriate antibiotics and supportive treatment, she continued to deteriorate and developed multiorgan dysfunction, leading to her demise.

摘要

恙虫病是一种由螨传播的立克次体感染,表现为发热及一系列不同的并发症。最近,印度次大陆报告了多起疫情。这些疫情的数据表明,恙虫病所致肝损伤很常见且可逆转。我们报告一例27岁的孕妇病例,该患者出现发热、脑病、黄疸及癫痫发作。入院时她已出现急性肝衰竭及死胎。尽管给予了适当的抗生素及支持治疗,她仍持续恶化并出现多器官功能障碍,最终死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aee1/7532875/6467cfeb0131/cureus-0012-00000010191-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aee1/7532875/6467cfeb0131/cureus-0012-00000010191-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aee1/7532875/6467cfeb0131/cureus-0012-00000010191-i01.jpg

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Clinical Profile and Outcome of Dengue Fever in Multidisciplinary Intensive Care Unit of a Tertiary Level Hospital in India.印度一家三级医院多学科重症监护病房登革热的临床特征与转归
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Acute Fatty Liver of Pregnancy: Pathophysiology, Anesthetic Implications, and Obstetrical Management.
恙虫病:慢性肝衰竭急性加重的一个诱因
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Oxf Med Case Reports. 2022 Sep 26;2022(9):omac092. doi: 10.1093/omcr/omac092. eCollection 2022 Sep.
妊娠急性脂肪肝:病理生理学、麻醉影响及产科处理
Anesthesiology. 2019 Mar;130(3):446-461. doi: 10.1097/ALN.0000000000002597.
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Med Hypotheses. 2018 Jun;115:61-64. doi: 10.1016/j.mehy.2018.03.019. Epub 2018 Mar 31.
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