Department of Chemistry, University of Houston, 4800 Calhoun Road, Houston, TX 77204, USA.
Chem Commun (Camb). 2020 Nov 11;56(87):13381-13384. doi: 10.1039/d0cc04970k. Epub 2020 Oct 9.
An organoiridium complex bearing a quinone moiety was shown to significantly accelerate the rate of HO formation in the presence of air and sodium formate at low catalyst concentrations. This reaction is proposed to operate through a synergistic mechanism involving transfer hydrogenation catalysis and radical chemistry. Our bifunctional iridium complex could potentially be used in anti-cancer chemotherapy or other applications requiring rapid generation of reactive oxygen species.
一种含有醌部分的有机铱配合物在低催化剂浓度下，在空气和甲酸钠存在的情况下，显著加速了 HO 的形成速率。该反应被认为是通过协同机制进行的，涉及转移氢化催化和自由基化学。我们的双功能铱配合物有可能用于癌症化疗或其他需要快速生成活性氧的应用。
